Journal List > J Korean Orthop Assoc > v.27(1) > 1114468

Lee, Lee, Jeon, and Min: The Effect Bone Cement in the Treatment of giant cell Tumor

Abstract

Giant cell tumor is a relatively rare tumor which is commonly found at the epiphysis of the long bones in the young age and adult. At the time of first detection, it usually shows destructive bony change and sometimes has potentially malignant character. So it is challenging to select the adequate method of treatment. It is reported that the method of curettage, curettage and bone graft result in high incidence of local recurrence. We expect that the bone cement may play a role as a space filler of bony defect after curettage of bony lesion and as a local cytotoxic agent by the heat generation during polymerization. We reviewed the 15 patients treated with curettage and bone cement filling during January, 1980 to December 1990 at the Seoul National University Hospital. The results were as follows. l. Among the 15 patients, male and female were 6 and 9 respectively. The average age was 29 years in male and 36 years in female. 2. The affected site was distal femur in 9 cases, proximal humerus in 3 cases, distal tibia in 2 cases, and proximal tibia in 1 case. 3. The follow-up period ranged from 1 year to 9 year 9 months, average 3 years and 4 months. 4. In 2 cases, lung metastasis was found, but the primary lesion did not show local recurrence during the follow-up period. 5. The complications were joint stiffness in 2 cases, pathologic fracture, and local recurrence in 1 case respectively. In the treatment of giant cell tumor of long bone which is large and destructive bony change around joint, curettage and bone cement filling is a good method of treatment when a curettage is not possible, and it results in low local recurrence rate, decreased limitation of ROM and permitts early weight bearing.

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