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Korean J Pediatr Gastroenterol Nutr. 2002 Mar;5(1):91-95. Korean.
Published online Mar 31, 2002.  https://doi.org/10.5223/kjpgn.2002.5.1.91
Copyright © 2002 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
A Case of Eosinophilic Colitis in a 11-year-old Boy
Joo Hee Nah, Young Shil Park, Sun Mi Kim, Jung Hyun Lee, Dae Chul Jeong, Jin Tack Kim, Seung Yun Chung, An Hi Lee,1 Jin Han Kang and Joon Sung Lee
Department of Pediatrics, The Catholic University of Korea College of Medicine, Seoul, Korea.
1Department of Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea.
Abstract

Eosinophilic gastroenteritis, which shows characteristic eosinophilic inflammation, involves any part of the intestine from esophagus to colon. The immunopathogenesis is expected to be associated with IgE-mediated or non-IgE-mediated reaction, but the precise mechanism is not revealed yet. The clinical manifestation is variably dependent on the extent of eosinophilic infiltration. Usually the symptoms, such as abdominal pain, diarrhea, vomiting, wax and wane for a few months result in failure to thrive, which implicates the importance of early detection. Although the diagnosis is made through clinical and histopathologic evidences, we should suspect the illness in a case of anemia, hypoalbuminemia, and peripheral eosinophilia. Recently, we experienced a case of non- IgE-mediated eosinophilic colitis in a 11-year-old male who complained of diarrhea, right lower abdominal pain, body weight loss, was diagnosed with peculiar histopathologic finding of sigmoid colon specimens obtained by sigmoidoscopy.

Keywords: Non-IgE-mediated; Eosinophilia