Journal List > Korean J Pediatr Gastroenterol Nutr > v.5(2) > 1110434

Korean J Pediatr Gastroenterol Nutr. 2002 Sep;5(2):199-205. Korean.
Published online Sep 30, 2002.  https://doi.org/10.5223/kjpgn.2002.5.2.199
Copyright © 2002 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
Neonatal Cholestasis Associated with Congenital Hypopituitarism
Hye Ran Yang, Eun Gyoung Song, Jeong Eun Kim, Su Jin Jeong, Gyoung Hoon Lee, Choong Ho Shin, Sei Won Yang, Jae Sung Ko, Gyeong Hoon Kang,* and Jeong Kee Seo
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
*Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Abstract

Congenital hypopituitarism is a possible cause of neonatal cholestasis, but the mechanism is still unknown. The pathogenesis of cholestasis may be due to hormone deficiency, which has effects on the physiological maturation of bile acid synthesis and transport. We experienced a case presenting with cholestasis and recurrent hypoglycemia associated with congenital hypopituitarism. Cholestasis resolved with thyroxine and hydrocortisone replacement therapy

Keywords: Neonatal cholestasis; Hypopituitarism; Hypoglycemia