Journal List > Korean J Pediatr Gastroenterol Nutr > v.8(1) > 1110304

Korean J Pediatr Gastroenterol Nutr. 2005 Mar;8(1):87-90. Korean.
Published online Mar 31, 2005.
Copyright © 2005 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
A Case of Neonatal Cholestasis Associated with Congenital Adrenal Hyperplasia
Seon Yun Choi, Jun Chul Byun, Won Joung Choi, Heung Sik Kim, Una Kang and Jin Bok Hwang
Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea.
Department of Pathology, Keimyung University School of Medicine, Daegu, Korea.

It has been suggested that cortisol deficiency may be responsible for the cholestasis. Although congenital hypopituitarism was reported as a possible cause of neonatal cholestasis, congenital adrenal hyperplasia with neonatal cholestasis is a very rare report in the literature. We experienced a case presenting with neonatal cholestasis associated with congenital adrenal hyperplasia. This case provides a clinical evidence supporting the notion that cortisol has an important physiological role in bile acid synthesis and transport.

Keywords: Neonatal cholestasis; Congenital adrenal hyperplasia