Journal List > Korean J Pediatr Gastroenterol Nutr > v.10(1) > 1110226

Korean J Pediatr Gastroenterol Nutr. 2007 Mar;10(1):91-97. Korean.
Published online Mar 31, 2007.  https://doi.org/10.5223/kjpgn.2007.10.1.91
Copyright © 2007 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
A Case of Chronic Lymphoplasmacellular Osteomyelitis with Autoimmune Hepatitis/Primary Sclerosing Cholangitis Overlap Syndrome in a Child
Ji Hyuk Lee, Hyun Young Lee, Jin Kyu Kim, Jee Hyun Lee and Yon Ho Choe
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan UniversitySchool of Medicine, Seoul, Korea.
Abstract

The Overlap syndrome is characterized by a combination of the major hepatobiliary autoimmune diseases such as autoimmune hepatitis, primary biliary cirrhosis and primary sclerosing cholangitis. It is frequently accompanied by inflammatory bowel disease. Chronic lymphoplasmacellular osteomyelitis is characterized by recurrent episodes of bacterial osteomyelitis and is associated with autoimmune diseases (especially inflammatory bowel disease). We report the case of a girl who was diagnosed with ulcerative colitis and autoimmune hepatitis at 4 years of age and with the overlap syndrome with primary sclerosing cholangitis at 6 years. At 9 years, she was diagnosed with chronic lymphoplasmacellular osteomyelitis.

Keywords: Overlap syndrome; Autoimmune hepatitis; Primary sclerosing cholangitis; Chronic lymphoplasmacellular osteomyelitis