Journal List > Korean J Pediatr Gastroenterol Nutr > v.10(2) > 1110195

Korean J Pediatr Gastroenterol Nutr. 2007 Sep;10(2):206-210. Korean.
Published online Sep 30, 2007.  https://doi.org/10.5223/kjpgn.2007.10.2.206
Copyright © 2007 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
Medulloblastoma and Familial Adenomatous Polyposis in a 24-year-old Female Patient: A Case Report of Turcot Syndrome
Soo In Jeong, Jung Min Suh, Ji Hyuk Lee, Hae Jung Lee, Jee Hyun Lee, Ki Woong Sung, Hye Jung Song,* and Yon Ho Choe
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
*Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Abstract

Turcot syndrome is characterized by the concurrence of a primary neuroepithelial brain tumor and multiple colorectal polyposis. We report a case of a 24-year-old woman diagnosed with Turcot syndrome. At first, the patient was diagnosed as having a medulloblastoma after a tumorectomy of the 4th ventricle mass. The patient underwent radiotherapy and chemotherapy. After high-dose chemotherapy, neutropenic fever and severe mucositis developed. For an evaluation of the persistent hematochezia and diarrhea, a colonoscopy was performed. It revealed pseudomembranous colitis and multiple polyps in the entire colon. According to the family history, her father had undergone a total colectomy due to colon cancer and polyposis of the entire colon. Her brother also was found to have multiple polyps in the colon by a colonoscopy. The patient was diagnosed with Turcot syndrome.

Keywords: Turcot syndrome; Medulloblastoma; Familial adenomatous polyposis