Journal List > Korean J Pediatr Gastroenterol Nutr > v.12(1) > 1110060

Korean J Pediatr Gastroenterol Nutr. 2009 Mar;12(1):46-50. Korean.
Published online Mar 31, 2009.  https://doi.org/10.5223/kjpgn.2009.12.1.46
Copyright © 2009 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
Candida Esophagitis in a Patient with Cowden's Syndrome: A Case Report
Kyung Ji Kang, Hye Jung Yun, Seong Yeol Ryu,* Nam Hee Ryoo, Yu Na Kang, and Jin Bok Hwang
Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea.
*Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Department of Diagnostic Laboratory, Keimyung University School of Medicine, Daegu, Korea.
Department of Pathology, Keimyung University School of Medicine, Daegu, Korea.
Abstract

Cowden's syndrome is a harmatomatous polyposis syndrome with characteristic mucocutaneous lesions and among the spectra of clinical disorders that has been attributed to germline mutations in the PTEN gene. Although Cowden's syndrome has rarely been reported, immunologic studies have revealed that patients with this syndrome have humoral and/or cellular immune abnormalities. We recently identified a 21-year-old woman with Cowden's syndrome who was diagnosed with candida esophagitis without a history of diabetes, carcinoma, or steroid therapy. We report the immunologic status of this patient and the relationship with candida esophagitis on the basis of a literature review.

Keywords: Cowden syndrome; Candida esophagitis; Immunologic abnormality