Journal List > Int J Thyroidol > v.11(2) > 1109129

Kim, Kang, Kim, Lee, Seo, and Park: A Case of Intrathyroid Thyroglossal Duct Cyst

초록

An intrathyroid thyroglossal duct cyst (TGDC) presented as an anterior neck mass in a 62-year-old male without history of prior thyroid disease or infection. This cyst was clinically indistinguishable from a thyroid nodule. In addition to that, fine needle aspiration cytology revealed normal– looking squamous cells. Diagnosis, work-up, management approach, and treatment of intrathyroid TGDC are discussed as well as distinguishing features between intrathyrod TGDC with tract and without tract. This is the very rare case of intrathyroid TGDC in Korean population and the possibility of intrathyroid TGDC should remain in the differential diagnosis of thyroid nodule.

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Fig. 1.
Thyroid ultrasound images and ultrasound guided fine-needle aspiration (FNA) image of left thyroid gland. 2.2×1.2×3.0 cm sized pre-dominantly cystic lesion (A). This FNA image is only liquid-based acellular specimen (B). After 1 year, 0.9×0.3×1.8 cm sized cystic lesion with calcified debri (C). Only visible many benign- looking squamous cells (D). After 2 years, 0.9×0.3×1.6 cm sized predominantly cystic lesion with calcified debris (E). This FNA image is visible few follicular cells (F).
ijt-11-167f1.tif
Fig. 2.
Computed tomography and light microscopic image of pathologic specimen. The hypodense lesion (white arrows) is located in the left thyroid gland. (A) Axial view,(B) Coronal view. Histopathological examination. Hema-toxylin-Eosion staining (H&E staining); the thyroid nodule showed the squamous epithelium lining and pseudo-stratified ciliated columnar cells with thyroid follicles in the sur-rounding colloid. (C) (x 100), (D) (x 400).
ijt-11-167f2.tif
Table 1.
Summary of cases of intrathyroid TGDC
Case Age/Sex (years) Symptom Preoperative fine needle aspiration cytology Thyroglossal duct tract Operation Sistrunk procedure Recurrence
1.4) 41/F Ant. neck mass Acellular specimen - Lt. hemithyroidectomy - ?
2.5) 9/M Lt. neck mass Normal appearing squamous epithelial cells and keratinaceous material Mass excision ?
3.6) 4/F Rt. thyroid nodule   Rt. hemithyroidectomy -
4.6) 9/F Lt. thyroid nodule   - Mass excision - -
5.7) 10/M Ant. neck mass Consistent with a TGDC - Lt. hemithyroidectomy, isthmusectomy - -
6.8) 45/F Ant. neck mass   - Lt. hemithyroidectomy - ?
7.9) 50/F Rt. neck mass Normal-looking squamous cells - Rt. hemithyroidectomy - -
8.10) 11/M Rt. neck mass Cells suggestive of a TGDC - Rt. hemithyroidectomy - -
9.12) 2/M Rt. neck mass   - Enucleation - ?
10.12) 10/M Rt. neck mass A squamous epithelium - Enucleation - ?
This study 62/M Ant. neck mass Benign-looking squamous cells and follicular cells - Lt. hemithyroidectomy, isthmusectomy - -

Ant.: anterior, F: female, Lt.: left, M: male, Rt.: right, TGDC: thyroglossal duct cyst

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