Platelet-Rich Plasma Injection

Jeong yong Yoon; Chris Hyunchul Jo

doi:10.4055/jkoa.2018.53.5.381

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Yoon and Jo: Platelet-Rich Plasma Injection

Symposium

Non-Operative Regenerative Therapy for Musculoskeletal Disorders

Journal of the Korean Orthopaedic Association 2018; 53(5): 381-392.

Published online: 31 October 2018

DOI: https://doi.org/10.4055/jkoa.2018.53.5.381

Platelet-Rich Plasma Injection

Jeong yong Yoon, M.D., Chris Hyunchul Jo, M.D.

Department of Orthopedic Surgery, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.

Correspondence to: Chris Hyunchul Jo, M.D. Department of Orthopedic Surgery, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul 07061, Korea. TEL: +82-2-870-2315, FAX: +82-2-870-3864, chrisjo@snu.ac.kr

Received 30 September 2017 Revised 2 January 2018 Accepted 20 June 2018

The Korean Orthopaedic Association

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Platelet-rich plasma (PRP) supplies numerous growth factors from concentrated platelets required to promote the healing process of injured or degenerated tissue. PRP is already a popular option to treat a variety of musculoskeletal injuries and diseases, even though the precise mechanism of action is not completely understood. Varying outcomes, from favorable to poor, after PRP injection may arise from interstudy differences with respect to 4Ds (Drug [PRP], Delivery [application method], Donor [patients], and Disease [stage of rotator cuff disease]). In addition, there is no standard treatment regimen (injection location, number, interval, volume). Therefore, precise outcome measures as well as long-term follow-up are required to accurately evaluate the efficacy.

Keywords: platelet-rich plasma, injection, osteoarthritis, tendinopathy, rotator cuff tear

Notes

^{CONFLICTS OF INTEREST} The authors have nothing to disclose

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