Most of health care professional obtain and update their new knowledge and skills through continuing education. Nurses who works three shifts per day are not easy to attend continuing education session usually offered during their working hours. One of solutions to this problem would be to develop a education program which does not limit time and place. The aim of this study is to develop and evaluate a web-based continuing education program, to help nurse improve their knowledge of transfusion therapy and medical law, and to enhance their ability to contribute to the quality of patient care. A wide range of contents regarding transfusion therapy are covered extensively, concentration on principles of transfusion therapy and administration of whole blood and blood components, transfusion reactions. In the medical law, contents on Korean law in general, medical law, history of revision of medical law, nursing related medical laws are covered, Many color illustrations have been included to help nurses learning process. Each unit has a set of multiple choice questions to provide feedback to nurses. Two sets of questionnaires were used for this study. First, a questionnaire was administered to 21 nurses to collect information on their general characteristics, opinions of inservice and continuing education, and experiences of using computer and internet before they were exposed to the program. Second, another questionnaire was administered to 21 nurses after they were exposed to the program. They were asked to evaluate program in terms of its easiness of use, contents and ways of presenting contents, and usefulness of program for learning. The program generally was well received by the nurses. The program is a useful adjunct to the existing continuing education program. It also could be used in nursing student education and other health sciences.