Medical images wit high resolution are coded to be archived communicated in PACS. In this pater, we have studied on coding of Cardio-Angiography. Our coding technique is method is Subband-Vector Quantization. This technique is irreversible coding method. This technique's objects are removing blocking artifact and edge degradation, adapting for drastic image change because of dye injection, and fast decoding, We achieved good results for Cardio-Angiography data, but the study on more sophisticated motion estimation techniques and VQ techniques must be performed.