Telemedicine is described as combination of topics from the fields of telecommunication, medicine, and information and literally telemedicine means medicine at a distance. In this study, we present a web based real-time telemedicine application(WEBRETA) that was designed for patients who needs diagnosis on the Internet. The WEBRETA system is supporting transmitting of MPEG-4 video format(640*480)that was appropriate for Internet and designed with ActiveX controls technology that is also suitable for telecommunication link such as ADSL, VDSL and Cable modem which are very popular communication link in Korea. To improve the reliability and the usefulness of this prototype we involved the PSNR method and subjective score measuring from doctors. Futhermore, we will evaluate the WEBRETA with various communication network environment to improve how this system can contribute the diagnosis of patients and to analysis.