Overview and challenges of current genetic research on allergic diseases in Korean children

Myunghyun Sohn

doi:10.4168/aard.2018.6.S1.S77

Journal List > Allergy Asthma Respir Dis > v.6(Suppl 1) > 1101966

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Sohn: Overview and challenges of current genetic research on allergic diseases in Korean children

Review

Allergy, Asthma & Respiratory Disease 2018; 6(Suppl 1): S77-S84.

Published online: 28 September 2018

DOI: https://doi.org/10.4168/aard.2018.6.S1.S77

Overview and challenges of current genetic research on allergic diseases in Korean children

Myunghyun Sohn

Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.

Correspondence to: Myunghyun Sohn. Department of Pediatrics, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. Tel: +82-2-2228-2050, Fax: +82-2-393-9118, mhsohn@yuhs.ac

Received 24 October 2017 Revised 8 January 2018 Accepted 10 January 2018

The Korean Academy of Pediatric Allergy and Respiratory Disease; The Korean Academy of Asthma, Allergy and Clinical Immunology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/).

Abstract

Since Cookson et al. first reported the association of atopy with chromosome 11q13 in 1989, there have been numerous studies of genetics for allergic diseases. Their aim is to identify genetic factors modifying susceptibility to allergic diseases, determining the severity of disease in affected individuals and affecting the response to treatment. With these efforts, allergic diseases can be termed complex genetic disorders, defined as disorders that have numerous contributing genes, each having variable degrees of involvement in any given individual. This review aims to provide information on the current state of genetic research in Korean pediatric allergic diseases.

Keywords: Genetics, Korea, Pediatrics, Allergy, Asthma

Figures and Tables

Table 1

Allergic disease susceptibility genes identified in Korean children

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ORCID iDs: Myunghyun Sohn
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