Palliative Transcatheter Arterial Chemoembolization for Relieving Metastatic Bone Pain due to Hepatocellular Carcinoma: A Case Report

Hye Ji Ryu; Sung Nam Moon; Nam Kyu Chang

doi:10.3348/jksr.2018.79.4.237

Journal List > J Korean Soc Radiol > v.79(4) > 1101840

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Ryu, Moon, and Chang: Palliative Transcatheter Arterial Chemoembolization for Relieving Metastatic Bone Pain due to Hepatocellular Carcinoma: A Case Report

Case Report

J Korean Soc Radiol 2018;79(4):237-241.

Published online: 19 January 2018

DOI: https://doi.org/10.3348/jksr.2018.79.4.237

Palliative Transcatheter Arterial Chemoembolization for Relieving Metastatic Bone Pain due to Hepatocellular Carcinoma: A Case Report

Hye Ji Ryu, MD¹, Sung Nam Moon, MD^1,, Nam Kyu Chang, MD²

¹Department of Radiology, Wonkwang University School of Medicine & Hospital, Iksan, Korea

²Department of Radiology, Yeonggwang Medical Center, Yeonggwang, Korea

^∗Corresponding author: Sung Nam Moon, MD Department of Radiology, Wonkwang University School of Medicine & Hospital, 895 Muwang-ro, Iksan 54538, Korea. Tel. 82-63-859-1920 Fax. 82-63-859-4749 E-mail:msnrage23@naver.com

Received 12 September 2017 Revised 15 May 2018 Accepted 22 May 2018

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Bone metastasis is the third most common extrahepatic metastasis from hepatocellular carcinoma (HCC), following lung and lymph node metastasis. Although transcatheter arterial chemoembolization (TACE) is widely used for the treatment for unresectable HCC in the liver, its effects on bone metastasis from HCC have not been well described in past literature. We report a case of a patient with a metastatic bone lesion from an HCC treated with TACE. After the procedure, the patient's pain and narcotic requirement significantly decreased without major complications.

Keywords: Chemoembolization, therapeutic, Hepatocellular Carcinoma, Bone Neoplasm

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Fig. 1

TACE of symptomatic bone metastasis from hepatocellular carcinoma in a 66-year-old man. A-C. In the selective arteriogram of the right intercostobronchial trunk (A), right 3rd (B), 4th and 5th (C) intercostal arteries, tumoral staining that correspond to the bone metastasis are seen. D. Completion angiogram after TACE using chemomixure of Adriamycin and lipiodol and gelfoam particle reveals > 75% reduction of tumor blush, which means technical success. TACE = transcatheter arterial chemoembolization TACE of symptomatic bone metastasis from hepatocellular carcinoma in a 66-year-old man. E. On follow-up CT after 3 months of TACE (right), size of the mass narrowing T3 spinal canal decreases and marginal shape of the mass changes to concave compared to CT before TACE (left). TACE = transcatheter arterial chemoembolization

Fig. 2

Total number of medication decreased with improved patient's pain after TACE as depicted in this graph. TACE = transcatheter arterial chemoembolization

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