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Abstract
Squamous cell carcinoma (SCC) of the pancreas is an extremely rare subtype of pancreatic cancer. To our best knowledge, magnetic resonance imaging findings, including diffusion weighted images and the non-hypervascular feature on computed tomography, in patients with SCC of the pancreas have not been reported previously. We present the computed tomography and magnetic resonance imaging findings of SCC of the pancreas in a 63-year-old male patient with no specific past history.
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Fig. 1
Squamous cell carcinoma of the pancreas in the 63-year-old male. A. Computed tomography findings show squamous cell carcinoma of the pancreas with splenic invasion and liver metastasis on the portal phase. B. Attenuation of this tumor does not increase from 35 HU to 61 HU on the arterial phase, and the finding is not typical in squamous cell carcinoma of the pancreas. C. T2WI shows a hyperintense mass and T1WI shows a hypointense mass. D. The tumor shows high signal intensity on the high-b-value (800 s/mm2) DWI and low signal intensity on the ADC map similar to the signal intensity of the spleen. ADC = apparent diffusion coefficient, AP = arterial phase, DWI = diffusion weighted image, HU = hounsfield unit, PP = portal phase, PRE = pre-contrast, T2WI = T2 weighted image, T1WI = T1 weighted image E. Endoscopic ultrasound shows a hypoechoic mass with the cystic portion in the pancreas tail (arrow). F. A microphotograph shows that the tumor has a keratin pearl, but no glandular component (H&E staining, × 200). The immunohistochemical staining shows a diffuse pattern positive for P63 (× 100) and CK5/6 (× 100). CK = Cytokeratin, H&E = hematoxylin and eosin
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