Multiple Pyoderma Gangrenosum in Ulcerative Colitis

Sung Bum Kim; Si Hyung Lee

doi:10.4166/kjg.2018.72.3.155

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Kim and Lee: Multiple Pyoderma Gangrenosum in Ulcerative Colitis

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The Korean Journal of Gastroenterology 2018; 72(3): 155-158.

Published online: 21 September 2018

DOI: https://doi.org/10.4166/kjg.2018.72.3.155

Multiple Pyoderma Gangrenosum in Ulcerative Colitis

Sung Bum Kim, Si Hyung Lee

Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.

Correspondence to: Si Hyung Lee, Department of Internal Medicine, Yeungnam University College of Medicine, 170 Hyeonchung-ro, Nam-gu, Daegu 42415, Korea. Tel: +82-53-620-3830, Fax: +82-53-654-8386, dr9696@nate.com

Korean Society of Gastroenterology

(open-access):

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Figures and Tables

Fig. 1

Abdominal computed tomography scan showed wall thickening of sigmoid colon and rectum (white arrows).

Fig. 2

Colonoscopy showed diffuse hyperemic mucosa with aphthous ulcers and mucosal edema and hemorrhages at sigmoid colon (A) and multiple deep ulcers with exudate at the rectum (B).

Fig. 3

Rectum biopsy showed lymphoplasmacytic infiltration, ulceration, and a few distorted crypts (H&E, ×10).

Fig. 4

On admission day 2, the patient presented painful nodules and erythematous lesions on his right knee (A) and left foot (B) that progressed rapidly to irregular ulcers.

Fig. 5

Biopsy specimen from the ulcer of the right knee showed granulation tissue, lymphocyte infiltration, and abscess formation (H&E, ×100) (A) and abundant neutrophilic infiltration, resulting in abscess formation (H&E, ×200) (B).

Fig. 6

Incision and drainage of skin lesions of the left thumb (A), foot (B), and right knee (C) was performed.

Fig. 7

Healing ulcers with crust and hyperpigmentation on the left thumb (A), foot (B), and right knee (C) after systemic steroid therapy.

Fig. 8

Follow up sigmoidoscopy after treatment shows ulcer scar and pseudo-polyps at sigmoid colon and rectum.

Notes

^{Financial support} This work was supported by the 2016 Yeungnam University Research Grant.

^{Conflict of interest} None.

References

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ORCID iDs: Si Hyung Lee
https://orcid.org/0000-0001-7221-7506
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