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Cho, Park, and Chung: The Risk Factor Analysis of Infectious Corneal Ulcers Leading to Eyeball Removal
Original Article
Journal of the Korean Ophthalmological Society

Journal of the Korean Ophthalmological Society 2008; 49(1): 34-39.

Published online: 20 January 2008

DOI: https://doi.org/10.3341/jkos.2008.49.1.34

The Risk Factor Analysis of Infectious Corneal Ulcers Leading to Eyeball Removal

Sang Hyun Cho, M.D., Joo Wan Park, M.D., Sung Kun Chung, M.D.

Department of Ophthalmology and Visual Science, St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Address reprint requests to Sung Kun Chung, M.D. Department of Ophthalmology, St. Mary's Hospital, College of Medicine, The Catholic University of Korea, #62 Yeouido-dong, Yungdeungpo-gu, Seoul 150-726, Korea. Tel: 82-2-3779-1848, Fax: 82-2-761-6869, eyedoc@catholic.ac.kr

Received 4 January 2007       Accepted 4 September 2007

Copyright © 2008 The Korean Ophthalmological Society

Abstract

Purpose

To determine the risk factors of corneal ulcers that require eyeball removal even when properly managed.

Methods

We performed a retrospective review of 30 patients (30 eyes) who were diagnosed with corneal ulcers and underwent eyeball removal, even though their cases were properly managed, between 1990 and July, 2005. The Patients included of 14 males and 16 females. The mean age of the patients was 61.6±12.2. The ages of 20 patients were between 60 and 79.

Results

Unknown (13/30 [43.4%]) was the most commonly identified predisposing factor. The other predisposing gactors were ocular trauma (10/30 [33.3%]); bullous keratopathy (3/30 [10%]); keratoplasty (1/30 [3.3%]); pterygium excision (1/30 [3.3%]); history of Mooren's ulcer (1/30 [3.3%]); and bee sting (1/30 [3.3%]). The visual acuity at the time of evisceration was LP (-) (14/30 [46.7%]); LP (+) (4/30 [13.3%]); and hand motion (12/30 [40%]). Organisms were cultured in 7 patient (23.3%). Among these patients, funguses were cultured in 4 patients, and bacteria were cultured in 3 patients. The most common causes of evisceration were perforation (13/30 [43.3%]); pain (7/30 [23.3%]); impending perforation (7/30 [23.3%]); phthisis bulbi (1/30 [3.3%]); and endophthalmitis (1/30 [3.3%]).

Conclusions

According to this study, old age, ocular surface and other ocular disease and the corneal ulcer caused by fungi are the risk factor that can lead to a condition that requires removal of the eyeball. Consequently, we should pay special attention to patients who have these risk factors.

Keywords: Corneal perforation, Corneal ulcer, Evisceration, Keratitis

Figures and Tables

Table 1
Patient data
jkos-49-34-i001

*: Light perception.

†: Hand motion.

‡: The case which is suspected fungal infection clinically but was not proved by culture.

Table 2
Distribution of age
jkos-49-34-i002
Table 3
Cause of corneal ulcer
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Table 4
Causes of Trauma
jkos-49-34-i004
Table 5
Visual acuity before evisceration
jkos-49-34-i005
Table 6
Causes of evisceration
jkos-49-34-i006

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