Eosinophilic Colitis

Ra Ri Cha; Hyo Jung An; Hyun Jin Kim

doi:10.4166/kjg.2018.72.2.90

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Cha, An, and Kim: Eosinophilic Colitis

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The Korean Journal of Gastroenterology 2018; 72(2): 90-92.

Published online: 23 August 2018

DOI: https://doi.org/10.4166/kjg.2018.72.2.90

Eosinophilic Colitis

Ra Ri Cha, Hyo Jung An¹, Hyun Jin Kim

Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, Korea.

¹Department of Pathology, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, Korea.

Correspondence to: Hyun Jin Kim, Department of Internal Medicine, Gyeongsang National University Changwon Hospital, 11 Samjeongja-ro, Seongsan-gu, Changwon 51472, Korea. Tel: +82-55-214-3710, Fax: +82-55-214-3250, imdrkim@naver.com

Korean Society of Gastroenterology

(open-access):

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Figures and Tables

Fig. 1

Colonoscopic finding of a patient with eosinophilic colitis showing non-specific inflammatory changes, mucosal edema, patchy eythema, and loss of vascularity. (A) Cecum. (B) Proximal ascending colon. (C) Upper rectum. (D) Lower rectum.

Fig. 2

Pathologic findings. (A) Microscopic findings show focal eosinophilic infiltration in the mucosal layer (H&Eosin stain, ×40). (B) In higher magnification, numerous eosinophils, up to 100/HPF are infiltrating to the lamina propria (H&E stain, ×400). HPF, high power field.

Fig. 3

Follow up sigmoidoscopy. Non-specific inflammatory mucosal lesion was improved compared with previous sigmoidoscopy. (A) Upper rectum. (B) Lower rectum.

Notes

^{Financial support} None.

^{Conflict of interest} None.

References

1. Fenoglio LM, Benedetti V, Rossi C, et al. Eosinophilic gastroenteritis with ascites: a case report and review of the literature. Dig Dis Sci. 2003; 48:1013–1020.

2. Rothenberg ME. Eosinophilic gastrointestinal disorders (EGID). J Allergy Clin Immunol. 2004; 113:11–28. quiz 29.

3. Gaertner WB, Macdonald JE, Kwaan MR, et al. Eosinophilic colitis: university of Minnesota experience and literature review. Gastroenterol Res Pract. 2011; 2011:857508.

4. Talley NJ, Shorter RG, Phillips SF, Zinsmeister AR. Eosinophilic gastroenteritis: a clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues. Gut. 1990; 31:54–58.

5. Khan S, Orenstein SR. Eosinophilic gastroenteritis. Gastroenterol Clin North Am. 2008; 37:333–348. v

6. Klein NC, Hargrove RL, Sleisenger MH, Jeffries GH. Eosinophilic gastroenteritis. Medicine (Baltimore). 1970; 49:299–319.

7. Cello JP. Eosinophilic gastroenteritis--a complex disease entity. Am J Med. 1979; 67:1097–1104.

8. Chen MJ, Chu CH, Lin SC, Shih SC, Wang TE. Eosinophilic gastroenteritis: clinical experience with 15 patients. World J Gastroenterol. 2003; 9:2813–2816.

9. Sundaram S, Sunku B, Nelson SP, et al. Adherent white plaques: an endoscopic finding in eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2004; 38:208–212.

10. Straumann A, Simon HU. The physiological and pathophysiological roles of eosinophils in the gastrointestinal tract. Allergy. 2004; 59:15–25.

11. Rubio CA. A method for the detection of eosinophilic granulocytes in colonoscopic biopsies from IBD patients. Pathol Res Pract. 2003; 199:145–150.

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