Journal List > Prog Med Phys > v.28(3) > 1098595

Cho, Cheon, Ahn, Lee, Park, and Han: Development of a Real-Time Internal and External Marker Based Gating System for Proton Therapy

Abstract

In respiratory-induced proton therapy, the accuracy of tracking system and beam controlling is more important than photon therapy. Therefore, a high accuracy motion tracking system that can track internal marker and external surrogate is needed. In this research, our team has installed internal and external marker tracking system at our institution's proton therapy system, and tested the scanning with gating according to the position of marker. The results demonstrate that the developed in-house external/internal marker based gating system can be clinically used for proton therapy system for moving tumor treatment.

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Fig. 1.
The flat panel detectors (FPD) at the gantry of our institution.
pmp-28-92f1.tif
Fig. 2.
The concept of finding the 3D coordinates of marker in biplane images (The two blue rectangles represent FPD's biplane images).
pmp-28-92f2.tif
Fig. 3.
The Bonita 10 camera (left) and the Nexus software (right).
pmp-28-92f3.tif
Fig. 4.
The real time output status of the ‘Co-registration Algorithm’. The boxes on the left side of the monitor show the coordinates of the three external markers, and the box on the right shows the 3D coordinates of the internal marker in millimeter scale.
pmp-28-92f4.tif
Fig. 5.
Current proton therapy system at our institution.
pmp-28-92f5.tif
Fig. 6.
Modified proton therapy system which is able to gate the beam based on external/internal marker's position.
pmp-28-92f6.tif
Fig. 7.
A sliding motion phantom was placed on a couch for phantom simulation.
pmp-28-92f7.tif
Fig. 8.
The gamma analysis result for case 1 with the anzai external respiratory gating.
pmp-28-92f8.tif
Fig. 9.
The gamma analysis result for case 1 with the modified system's respiratory gating.
pmp-28-92f9.tif
Fig. 10.
The gamma analysis result for case 2 with the anzai external respiratory gating.
pmp-28-92f10.tif
Fig. 11.
The gamma analysis result for case 2 with the modified system's respiratory gating.
pmp-28-92f11.tif
Table 1.
The gamma analysis comparison table
Gating method Passing rate Absolute difference (arithmetic mean)
Plan 1    
Anzai gating 89.0% 0.056 Gy
Gating with proposed system 93.8% 0.047 Gy
Plan 2    
Anzai gating 96.0% 0.044 Gy
Gating with proposed system 90.7% 0.045 Gy
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