Journal List > Prog Med Phys > v.26(1) > 1098501

Jung, Cho, Moon, Bae, Min, Kim, Yeo, Choi, Jung, Choe, and Suh: Rotation Errors of Breast Cancer on 3D-CRT in TomoDirect

Abstract

The purpose of this study was to analyze the rotational errors of roll, pitch, and yaw in the whole breast cancer treated by the three-dimensional radiation therapy (3D-CRT) using TomoDirect (TD). Twenty-patient previously treated with TD 3D-CRT was selected. We performed a retrospective clinical analysis based on 80 images of megavoltage computed tomography (MVCT) including the systematic and random variation with patient setup errors and treatment setup margin (mm). In addition, a rotational error (degree) for each patient was analyzed using the automatic image registration. The treatment margin of X, Y, and Z directions were 4.2 mm, 6.2 mm, and 6.4 mm, respectively. The mean value of the rotational error for roll, pitch, and yaw were 0.3°, 0.5°, 0.1°, and all of systematic and random error was within 1.0°. The errors of patient positioning with the Y and Z directions have generally been mainly higher than the X direction. The percentage in treatment fractions in less than 2° at roll, pitch, and yaw are 95.1%, 98.8%, and 97.5%, respectively. However, the edge of upper and lower (i.e., bottom) based on the center of therapy region (point) will quite a possibility that it is expected to twist even longer as the length of treatment region. The patient-specific characters should be considered for the accuracy and reproducibility of treatment and it is necessary to confirm periodically the rotational errors, including patient repositioning and repeating MVCT scan.

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Fig. 1.
Percentage of distribution in treatment fractions of the rotational errors in overall patients that roll, pitch, and yaw in less than 2°are 95.1%, 98.8%, and 97.5%, respectively.
pmp-26-6f1.tif
Table 1.
Patient setup errors and calculated treatment setup margin (mm) for 20 breast cancer.
Directions Mean (M) Systematic error (σ) Random error (Σ) Setup margin (mm) Maximum displacement
X (mm) -0.4 1.4 1.5 4.5 3.9
Y (mm) -0.8 1.9 2.0 6.2 -7.9
Z (mm) 1.0 2.0 2.0 6.4 6.7
Roll (°) 0.3 0.4 0.5 N/A 1.5

N/A: not applicable.

Table 2.
Magnitude of the translational and rotational adjustment by the automatic image registration.
Adjustments s Mean (M) Systematic error (σ) Random error (Σ) Maximum displacement
Translation (mm) X -0.5 1.5 1.7 -7.0
Y -1.4 2.7 1.9 -7.6
Z 1.9 2.3 2.0 7.9
Rotation (°) Roll 0.3 0.9 0.7 3.5
Pitch 0.5 0.6 0.5 2.2
Yaw 0.1 0.8 0.6 3.0
Table 3.
Correlations between the translational and rotational adjustment of 20 patients.
Inter-construct correlations
Directions
Directions X Y Z Roll Pitch Yaw
X 1.00          
Y 0.01 1.00        
Z - -0.05 -0.04 1.00      
Roll 0.07 -0.26∗ 0.09 1.00    
Pitch Yaw - 0.13 -0.30 -0.34 0.24∗ 0.30 -0.06 0.30 -0.22 1.00 -0.28∗ 1.00

Significance of these differences (P<0.05),

Significance of these differences (P<0.001).

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