The automated dental cavity detection program for a new concept intra-oral dental x-ray imaging device, an auxiliary diagnosis system, which is able to assist a dentist to identify dental caries in an early stage and to make an accurate diagnosis, was to be developed. The primary theory of the automatic dental cavity detection program is divided into two algorithms; one is an image segmentation skill to discriminate between a dental cavity and a normal tooth and the other is a computational method to analyze feature of an tooth image and take an advantage of it for detection of dental cavities. In the present study, it is, first, evaluated how accurately the DRLSE (Direct Regularized Level Set Evolution) method extracts demarcation surrounding the dental cavity. In order to evaluate the ability of the developed algorithm to automatically detect dental cavities, 7 tooth phantoms from incisor to molar were fabricated which contained a various form of cavities. Then, dental cavities in the tooth phantom images were analyzed with the developed algorithm. Except for two cavities whose contours were identified partially, the contours of 12 cavities were correctly discriminated by the automated dental caries detection program, which, consequently, proved the practical feasibility of the automatic dental lesion detection algorithm. However, an efficient and enhanced algorithm is required for its application to the actual dental diagnosis since shapes or conditions of the dental caries are different between individuals and complicated. In the future, the automatic dental cavity detection system will be improved adding pattern recognition or machine learning based algorithm which can deal with information of tooth status.