Journal List > Prog Med Phys > v.26(4) > 1098488

Jeong, Yoon, Kim, Chung, Chung, and Choi: Feasibility Study for Development of Transit Dosimetry Based Patient Dose Verification System Using the Glass Dosimeter

Abstract

As radiation therapy is one of three major cancer treatment methods, many cancer patients get radiation therapy. To exposure as much radiation to cancer while normal tissues near tumor get little radiation, medical physicists make a radiotherapy plan treatment and perform quality assurance before patient treatment. Despite these efforts, unintended medical accidents can occur by some errors. In order to solve the problem, patient internal dose reconstruction methods by measuring transit dose are suggested. As feasibility study for development of patient dose verification system, inverse square law, percentage depth dose and scatter factor are used to calculate dose in the water-equivalent homogeneous phantom. As a calibration results of ionization chamber and glass dosimeter to transit radiation, signals of glass dosimeter are 0.824 times at 6 MV and 0.736 times at 10 MV compared to dose measured by ionization chamber. Average scatter factor is 1.4 and Mayneord F factor was used to apply percentage depth dose data. When we verified the algorithm using the water-equivalent homogeneous phantom, maximum error was 1.65%.

References

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Fig. 1.
(a) The outline of experimental setting for dose calculation in the homogeneous phantom using the transit dose and (b) beam quality correction method of ionization chamber using IAEA TRS-398. Each Ks, Ts, f and d represent an amount of scattered dose to the bottom point, an amount of scattered dose to the transit dose measurement point, source to surface distance (SSD) and phantom thickness. Phantom dose can be calculated by measured transit dose multiplied by inverse square law factor and percentage depth dose data.
pmp-26-241f1.tif
Fig. 2.
Measurement of transit radiation dose according to variation of radiation energy, field size and monitor unit using the correction completed ionization chamber to transit radiation. (a) MU dependency at 10 cm phantom (b) MU dependency at 20 cm phantom (c) MU dependency at 30 cm phantom (d) Field size dependency at 10 cm (e) Field size dependency at 20 cm (f) Field size dependency at 30 cm.
pmp-26-241f2.tif
Fig. 3.
(a) 6 MV transit dose measurement results and (b) 10 MV transit dose measurement results measured by glass dosimeter of field size 4 cm×4 cm (◆), 10 cm×10 cm (■), 20 cm×20 cm (▲).
pmp-26-241f3.tif
Fig. 4.
Scatter factor measurement results of (a) 6 MV photon energy and (b) 10 MV photon energy when phantom thicknesses are 10 cm (◆), 20 cm (■), 30 cm (▲).
pmp-26-241f4.tif
Fig. 5.
Dose variation due to positional change of phantom center to isocenter. Relative dose change when the phantom center is above the isocenter (positive side of horizontal axis), below the isocenter (negative side of horizaontal axis) and on the isocenter (0). The results of (a) 6 MV 10 cm, (b) 6 MV 20 cm, (c) 6 MV 30 cm, (d) 10 MV 10 cm, (e) 10 MV 20 cm, (f) 10 MV 30 cm when field sizes are 4 cm×4 cm (◆), 10 cm×10 cm (■), 20 cm×20 cm (▲).
pmp-26-241f5.tif
Table 1.
The comparison of ionization chamber correction between transit dose result and original TRS-398 result.
    Radiation energy and phantom thickness  
Condition Correction factor   6 MV     10 MV  
  10 cm 20 cm 30 cm 10 cm 20 cm 30 cm
Transit Ndw 4.813 4.813 4.813 4.813 4.813 4.813
radiation Beam quality factor 0.991 0.989 0.988 0.980 0.975 0.977
Polarization correction 1.000 0.999 1.001 1.000 1.000 1.001
Recombination correction 1.000 1.002 1.003 1.001 1.002 1.003
TemperatureㆍPressure Correction 1.027 1.027 1.027 1.027 1.027 1.027
Original Ndw   4.813     4.813  
TRS-398 Beam quality factor   0.996     0.985  
Polarization correction   1.000     1.001  
Recombination correction   1.004     1.002  
TemperatureㆍPressure Correction   1.027     1.027  
Table 2.
The comparison between real measurement results at the center and bottom of 10 cm, 20 cm, 30 cm phantom and calculation results using the Mayneord F factor.
Phantom thickness Measurement point Measured dose (cGy) Maximum dose (cGy) Measured PDD Mayneord F factor PDD data Calculated PDD Difference (%)
10 cm Center 188.0 218.3 0.861 0.997 0.855 0.852 1.09
  Bottom 142.1 218.3 0.651 0.992 0.661 0.656 −0.73
20 cm Center 157.8 243.2 0.649 0.983 0.661 0.650 −0.19
  Bottom 86.8 243.2 0.357 0.967 0.380 0.368 −2.93
30 cm Center 129.3 272.7 0.474 0.960 0.502 0.482 −1.63
  Bottom 52.7 272.7 0.193 0.928 0.219 0.203 −4.99
Table 3.
Measurement result of transit radiation and comparison of calculation results using the 6 MV photon.
Phantom Transit Inverse square Scatter Bottom Center Calculated Measured Difference
thickness dose (cGy) law factor factor PDD PDD dose (cGy) dose (cGy) (%)
10 cm 52.16 2.041 1.335 0.651 0.861 187.95 186.94 0.54
20 cm 33.58 1.860 1.394 0.357 0.649 158.24 156.62 1.03
30 cm 22.16 1.701 1.403 0.193 0.474 129.91 132.09 −1.65
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