Abstract
The Cs-137 irradiator is widely used to irradiate biological samples for radiobiological research. To obtain the accurate outcomes, correct measurements of the delivered absorbed dose to a sample is important. The IAEA protocols such as TRS-277 and TRS-398 were recommended for the Cs-137 reference dosimetry. However in TRS-398 protocol, currently known as the most practical dosimetry protocol, the quality factor () for Cs-137 gamma rays is not suggested. Therefore, the use of TRS-398 protocol is currently unavailable for the Cs-137 dosimetry directly. The calculation method previously introduced for high energy photon beams in radiotherapy was used for deriving the Cs-137 beam qualities () for the 15 commercially available farmer type ionization chambers in this study. In conclusion, values were ranged from 0.998 to 1.002 for Cs-137 gamma rays. These results can be used as the reference and dosimeter calibrations for Cs-137 gamma rays in the future radiobiological researches.
References
1. Brady SL, Toncheva G, Dewhirst MW, Yoshizumi TT. Characterization of a 137Cs irradiator from a new perspective with modern dosimetric tools. Health Phys. 7(3):195–205. 2009.
2. Sabine H. Methods in Radiobiology. Nanodosimetry Workshop (. 2009.
3. Jeong DH, Kim JK, Yang KM, et al. Absorbed dose determination for a biological sample irradiated by gamma rays from a Cs-137 source. Korean J Med Phys. 22(3):124–130. 2011.
4. Moon YM, Kang YR, Kim JK, et al. Measurement of absorbed dose in mice using Glass Dosimeter implantation. Proceeding of KSMP spring meeting: 86–86 (. 2012.
5. Moon YM, Rhee DJ, Kim JK, at al: Reference Dosimetry and Calibration of Glass Dosimeters for Cs-137 Gamma-rays. Progress in Medical Physics. 24(3):140–143. 2013.
6. TRS-277: Absorbed Dose Determination in Photon and Electron Beams: An International Code of Practice. International Atomic Energy Agency, Vienna (. 1997.
7. TRS-398: Absorbed dose determination in external beam radiotherapy: an international code of practice for dosimetry based on standards of absorbed dose to water. International Atomic Energy Agency, Vienna (. 2000.
8. Jeong DH, Shin KC, Oh YK, et al. Direct calculation of TRS-398 quality correction factors for high energy photons. Korean J Med Phys. 17(1):54–60. 2006.
9. Kang YR, Lee CY, Kim JH. Study on the Evaluation of TRS-398 Quality Factors with Central Electrode Corrections for Small Cylindrical Chambers. Korean J Med Phys. 22(3):148–154. 2011.
10. Andreo P, Nahum AE, Brahme A. Chamber-dependent wall correction factors in dosimetry. Phys Med Biol. 31:1189–1199. 1986.
11. Muir BR, Rogers DWO. The central electrode correction factor for high-Z electrodes in small ionization chambers, Med Phys. 38(2):1081–1088. 2011.
12. Andreo P. Improved calculations of stopping-power ratios and their correlation with the quality of therapeutic photon beams, Measurement Assurance in Dosimetry(Proc. Symp. Vienna, 1993), IAEA, Vienna: 335–359 (. 1994.