Perianal streptococcal dermatitis is a bright red, sharply demarcated, perianal rash that is caused by group A beta-hemolytic streptococci. It primarily occurs in children between six months and 10 years of age and is often misdiagnosed and treated inappropriately. We report a case of Perianal streptococcal dermatitis in a 13-months-old female patient. A culture of the perianal area grew group A beta-hemolytic streptococcus. The patient was given systemic antibiotics and topical applications of mupirocin, and a dramatic improvement was noted.