Journal List > Korean J Pediatr Infect Dis > v.14(2) > 1096179

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Choi, Pak, Jung, Lee, Sun, Kim, Kim, Kim, Seo, and Chung: Clinical manifestation of human bocavirus infection in children
Original Article

Korean Journal of Pediatric Infectious Diseases 2007; 14(2): 136-144.

Published online: 30 November 2007

DOI: https://doi.org/10.14776/kjpid.2007.14.2.136

Clinical manifestation of human bocavirus infection in children

Chang Sun Choi, M.D., Chan Hee Pak, M.D., Kwan Jung, M.D., Gun Lee, M.D., Kyu Keun Sun, M.D., Eun Young Kim, M.D., Kyoung Sim Kim, M.D., Yong Wook Kim, M.D., Jin-Jong Seo, M.D.*, Yoon-Seok Chung, M.D.†

Department of Pediatrics, Kwang-Ju Christian Hospital, Korea.

*Division of Microbiology Department of Health Science, Gwangju City Health and Environment Research Institute, Korea.

†Division of Influenza and Respiratory viruses, Center for Infectious Disease, National Institute of Health, Korea Center for Disease Control and Prevention, Korea.

Corresponding author (kskim000@naver.com)

Copyright © 2007 The Korean Society of Pediatric Infectious Diseases

Abstract

Purpose

Human bocavirus (HBoV) was recently identified world widely in clinical specimens from infants and children with respiratory tract illness, but the role of HBoV in respiratory tract illnesses is unknown. The aim of this study was to investigate the frequency and the clinical manifestation of HBoV in pediatric patients.

Methods

We retrospectively investigated 1,777 throat swab obtained between 2005 and 2006 from pediatric in-patients with acute respiratory tract diseases at the Kwang-ju Christian Hospital. The medical records of patients with positive results were reviewed for demographic and clinical data of HBoV infections.

Results

HBoV DNA was found in 84 (4.7%) of the 1,777 hospitalized children and the mean age was 19 months. The most common diagnosis were pneumonia (67.8%), bronchiolitis (35.7%). HBoV infections were found year-round, though most occurred in spring and winter months.

Conclusion

HBoV is frequently found in hospitalized infants and children with acute respiratory tract diseases in Korea, but an association of HBoV with a distinct respiratory tract manifestation was not apparent. To clarify the clinical significance of HBoV, further evaluation of various age groups and clinical groups is needed.

Keywords: Respiratory infection, Human Bocavirus, Children, Clinical manifestation

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