Journal List > Pediatr Infect Vaccine > v.22(2) > 1096000

Kim, Kim, Kim, Jang, LeeA, Kim, Han, Kim, and Jang: A Small Outbreak of Measles in 2013: In a Single Hospital in Northern Gyeonggi-do

Abstract

Purpose

This study analyzed a small outbreak of measles at a single hospital located in northern Gyeonggi-do in 2013.

Methods

We reviewed the medical records of measles patients at The Catholic University of Korea Uijeongbu St. Mary's Hospital from August to October, 2013.

Results

Fifteen children were confirmed to have measles by RT—PCR and serum IgM test; 1 neonate, 11 infants, and 3 toddlers. None of the patients had received Measles—Mumps-Rubella vaccination. All patients showed B3 type in viral genotyping. Nine children (60%) had been exposed to measles during treatment for other diseases in the pediatric ward. Incubation period was between 8 and 15 days. Fever started at a median 10 days after exposure and persisted for a median of 8 days. Rash showed at a median 13 days after exposure. Respiratory complications were observed in 40% of patients. Diarrhea developed in 53% of patients.

Conclusion

Although measles has been well—controlled due to the high rate of vaccination coverage, it is possible to have an outbreak at any given time, especially in infants. We must learn from this outbreak, and remain fully aware of the possibility of reemergence and provide proper management, including vaccination or immune globulin administration, to infants exposed to measles. Reevaluation of serum lgG titer of neonates, infants, and pregnant women may be the first step to prevent further outbreaks.

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Fig. 1.
Measles cases by week during the outbreak.
piv-22-63f1.tif
Table 1.
Characteristics of Measles Patients at Diaanosis
ICase Sex Age (mo) MMR vaccination Infection route Fever duration (days) Complications
1 M 15 Not done Unknown 12 Diarrhea
2 F 8 Not done Nosocomial, from case 1 10 Pneumonia. Diarrhea
3 F 9 Not done Nosocomial. from case 2 6 Pneumonia
4 F 9.5 Not done Nosocomial, from case 2 >4 Diarrhea
5 M 8.5 Not done Nosocomial, from case 2 >4 None
6 M 9.5 Not done Nosocomial, from case 3 14 Pneumonia, Diarrhea
7 F 12 Not done Nosocomial, from case 3 7 Diarrhea
8 F 16 Not done Nosocomial, from case 3 11 None
9 F 9.5 Not done Nosocomial, from case 3 7 Diarrhea
10 M 5 Not done Nosocomial, from case 3 8 Bronchiolitis
11 F 8 Not done Household soread 6 Diarrhea
12 M 0.2 Not done Household spread 0 None
13 M 6.5 Not done Household spread 7 Bronchiolitis, Diarrhea
14 F 7.5 Not done Household spread 11 None
15 M 5.5 Not done Twin brother, from case 10 8 Bronchiolitis

Abbreviation: mo, months; MMR, measles-mumps-rubella.

Fever duration of patient No 4 and 5 could not be calculated because of lost to follow-up.

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