Severe Cytomegalovirus Infection in a Late-Preterm Infant at 2 Months of Age

Seo Yeol Choi; Kun Song Lee

doi:10.14776/piv.2016.23.2.137

Journal List > Pediatr Infect Vaccine > v.23(2) > 1095942

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Choi and Lee: Severe Cytomegalovirus Infection in a Late-Preterm Infant at 2 Months of Age

Case Report

Pediatric Infection & Vaccine 2016; 23(2): 137-142.

Published online: 25 August 2016

DOI: https://doi.org/10.14776/piv.2016.23.2.137

Severe Cytomegalovirus Infection in a Late-Preterm Infant at 2 Months of Age

Seo Yeol Choi, Kun Song Lee

Department of Pediatrics, College of Medicine, Dankook University, Cheonan, Korea.

Corresponding author (pdlks@dankook.ac.kr)

Received 2 November 2015 Revised 1 January 2016 Accepted 11 February 2016

Abstract

Severe cytomegalovirus (CMV) infection involving multiorgan is very rare except in very low-birth weight infants, or in immunocompromised pediatric patients. We report an unusual case of severe CMV infection involving multiple organs including the central nervous system, liver, lung, and gastrointestinal tract in a late-preterm infant at 2 months of age.

Keywords: Cytomegalovirus infection, Infant

Figures and Tables

Fig. 1

The brain magnetic resonance imaging (MRI) show high signal change at T1 weighted image, T2 weighted image (A, B) and high apparent diffusion coefficient (ADC) value at ADC map (C) in left postcentral gyrus (yellow arrow). These lesions were suspected with focal encephalitis with hemorrhage. After four months, follow up MRI show slightly improved focal encephalitis (D, E and F and T1, T2 weighted image and ADC map, respectively).

Fig. 2

The chest x-ray shows increased haziness in central area of both lungs.

Fig. 3

The esophagogastroduodenoscopy shows isolated erosive gastric mucosal lesions with hemorrhage on mid body of stomach.

Fig. 4

The graph and table shows the clinical progress and laboratory data. Ganciclovir administration was started at four days after admission. Thereafter, fever and laboratory data improved.

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