Etiology and Clinical Features of Acute Bacterial Gastroenteritis in Children Mananged at a Secondary Hospital

Sung Yoon Kim; Hyun-Jung Kim; Eun Hye Shin; Byung Wook Eun; Young Min Ahn; Mi Ok Song

doi:10.14776/piv.2017.24.2.95

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Kim, Kim, Shin, Eun, Ahn, and Song: Etiology and Clinical Features of Acute Bacterial Gastroenteritis in Children Mananged at a Secondary Hospital

Original Article

Pediatric Infection & Vaccine 2017; 24(2): 95-101.

Published online: 25 August 2017

DOI: https://doi.org/10.14776/piv.2017.24.2.95

Etiology and Clinical Features of Acute Bacterial Gastroenteritis in Children Mananged at a Secondary Hospital

Sung Yoon Kim¹, Hyun-Jung Kim¹, Eun Hye Shin¹, Byung Wook Eun^1,², Young Min Ahn^1,², Mi Ok Song³

¹Department of Pediatrics, Eulji General Hospital, Eulji University School of Medicine, Seoul, the Republic of Korea.

²Department of Pediatrics, Eulji University School of Medicine, Daejeon, the Republic of Korea.

³Infectious Disease Team, Seoul Metropolitan Government Research Institute of Public Health and Environment, Seoul, the Republic of Korea.

Corresponding author (acet0125@eulji.ac.kr)

Received 22 September 2016 Revised 17 October 2016 Accepted 17 October 2016

Abstract

Purpose

Acute bacterial gastroenteritis (ABG) can cause more severe symptoms than acute viral gastroenteritis in children. This study was aimed at determining the etiologic trends and to examine the clinical characteristics of ABG in children.

Methods

We sent stool samples from the children with acute gastroenteritis who were treated at a secondary hospital located in Seoul, Korea between January 2011 and December 2014 to Seoul Metropolitan Government Research Institute of Public Health and Environment to find the causative organisms. Clinical characteristics of patient were analyzed through a medical records review.

Results

Out of 664 stool samples, 183 (27.6%) yielded bacterial pathogens. Staphylococcus aureus was the most common bacterial pathogen, found in 72 cases (39.3%), even though it was only tested for since 2012. The monthly isolation rate was the highest (24.6%) in August. The isolation rate of Campylobacter spp. by patient's age group was high (16.7%) in the 12- to 18-year-age group (P=0.04). In patients with bloody stool, Campylobacter spp. was the most commonly isolated (31.0%, P=0.04). When comparing C-reactive protein, the Salmonella spp.- or Campylobacter spp.-isolated group showed higher values than the S. aureus- or pathogenic Escherichia coli-isolated group (5.7±0.6 mg/dL vs. 2.1±0.3 mg/dL, P<0.01).

Conclusions

S. aureus, Salmonella spp., pathogenic E. coli , and Campylobacter spp. were important pathogens of ABG among children. Considering the differences in pathogens found according to age, a clinical symptom and inflammation index might be helpful in assuming the causative organism.

Keywords: Gastroenteritis, Bacteria, Staphylococcus aureus, Campylobacter, C-reactive protein

Figures and Tables

Fig. 1

Monthly distribution of major bacterial pathogens and isolation rate of all causative bacteria isolated from children with acute diarrhea between January 2011 and December 2014.

Table 1

Trends of Enteropathogenic Bacteria Isolates from Children with Acute Diarrhea Between 2011 and 2014

Values are presented as number (%).

Table 2

Clinical Symptoms and Laboratory Data According to the Major Enteropathogenic Pathogens

Values are presented as number (%), median (range), or mean±standard deviation.

Abbreviations: WBC, white blood cell; CRP, C-reactive protein.

Table 3

Age Distribution of the Patients from Whom Enteropathogenic Bacteria Was Isolated

Values are presented as number (%).

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