Small Cell Carcinoma of the Ovary Hypercalcemic Type: A Case Report

Yeo Kyoung Nam; See Hyung Kim; Mi Sun Choi

doi:10.3348/jksr.2018.78.6.422

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Nam, Kim, and Choi: Small Cell Carcinoma of the Ovary Hypercalcemic Type: A Case Report

Case Report

J Korean Soc Radiol 2018;78(6):422-425.

Published online: 20 January 2018

DOI: https://doi.org/10.3348/jksr.2018.78.6.422

Small Cell Carcinoma of the Ovary Hypercalcemic Type: A Case Report

Yeo Kyoung Nam, MD¹, See Hyung Kim, MD^1,^∗, Mi Sun Choi, MD²

¹Department of Radiology, Keimyung University School of Medicine, Dongsan Medical Center, Daegu, Korea

²Department of Pathology, Keimyung University School of Medicine, Dongsan Medical Center, Daegu, Korea

^∗Corresponding author: See Hyung Kim, MD Department of Radiology, Keimyung University School of Medicine, Dongsan Medical Center, 56 Dalseong-ro, Jung-gu, Daegu 41931, Korea. Tel. 82-53-250-7767 Fax. 82-53-250-7766 E-mail: kseehdr@dsmc.or.kr

Received 18 July 2017 Revised 5 October 2017 Accepted 30 November 2017

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Small cell carcinoma of the ovary, hypercalcemic type is a rare ovarian tumor. This tumor has three distinctive clinical features: i) an occurrence in young women, ii) the presence of hypercalcemia in 62% of cases, and iii) a high degree of malignancy. The radiologic findings of the tumors are usually large and a predominantly solid mass with internal necrosis, hemorrhage and cystic degeneration. We report on the CT and MRI findings of an ovarian small cell carcinoma, hypercalcemic type in a 17-year-old female who presented 1 month abdominal discomfort with weight loss.

Keywords: Index terms Ovarian Cancer Small Cell Carcinoma Hypercalcemia Ovarian Neoplasm

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Fig. 1.

A 17-year-old female with ovarian masses detected on the CT scan. A. This contrast enhanced CT scan of the ovarian small cell carcinoma shows an approximately 15 cm sized heterogeneous mass in the pelvic cavity. B. The axial T2-weighted MR image shows a multiseptated mass with an increased signal intensity, suggesting an internal cystic change or necrosis. C. The axial T1-weighted MR image shows a heterogeneous low signal intensity mass. D. The axial T1-weighted contrast enhanced MR image shows a peripheral solid portion with enhancement. E. Gross picture of the ovarian small cell carcinoma shows a pale, white to gray solid mass with foci of cystic change, hemorrhage, and necrosis. F. The tumor cells are relatively monotonous and show scanty cytoplasm (hematoxylin and eosin stain, × 400).

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