Journal List > Allergy Asthma Respir Dis > v.3(1) > 1094431

Lee, Choi, Park, Kim, Kim, Park, Lee, Han, Chae, Ham, Lee, Kwon, and Ahn: Analysis of regional prevalence of allergic diseases in Korean school children

Abstract

Purpose

This study aimed to analyze the prevalence of allergic diseases in Korean schoolchildren according to their residential areas in 2010.

Methods

A nationwide, cross-sectional study was conducted in children aged 6–7 years (n=4,003) and adolescents aged 12–13 years (n=4,112) who were randomly selected. Demographic and disease-related information was obtained through a Korean version of ISAAC (International Study of Asthma and Allergies in Childhood) questionnaire, and skin prick tests for 18 inhalant allergens were performed.

Results

There was statistically significant regional difference in the prevalence of allergic rhinitis (AR) (P<0.05). The regions with highest and lowest prevalence in 12- to 13-year-old children were as follows: Chungcheong and Honam in “Diagnosis of AR, ever”(33.7% vs. 24.5%), Jeju and Yeongnam in “Treatment of AR, last 12 months” (25.5% vs. 18.0%), Chungcheong and Yeongnam in “Rhinitis with sensitization” (31.6% vs. 23.6%). The regions with highest and lowest prevalence in 6–7 years old children were as follows: Yeongnam and Seoul in “Diagnosis of AR, ever” (42.1% vs. 31.0%), Yeongnam and Jeju in “Treatment of AR, last 12 months” (31.8% vs. 21.9%), Jeju and Seoul in “Rhinitis with sensitization” (26.0% vs. 18.4%). We also found a regional difference in inhalant allergens among the children with “rhinitis with sensitization”.

Conclusion

The prevalence of AR in children differs according to residential areas in a nationwide survey in 2010 while there is no significant regional difference in the prevalence of asthma and AD.

References

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Fig. 1.
Sensitization rate to inhalant allergens according to residential areas in children aged 6–7 years (A–C) and 12–13 years (D–F) with “rhinitis with sensitization”. Data on indoor allergens (A, D) are presented, while the distribution of sensitization to tree pollen and grass pollen (B, E) along with weed pollen and fungi (C, F) are shown as well. ∗ P<0.05. Der p, Dermatophagoides pteronyssinus; Der f, Dermatophagoides farina; Tyro p, Tyrophagus putrescentiae.
aard-3-62f1.tif
Table 1.
Demographic characteristics of study population
Characteristic 6–7 years (n=4,003) 12–13 years (n=4,112)
Gender, male/female 2,021/1,982 2,029/2,083
Monthly income (KRW)    
≤1,990,000 546 (14.1) 616 (15.7)
2,000,000–3,990,000 1,939 (49.9) 1,689 (43.2)
4,000,000–5,990,000 982 (25.3) 1,074 (27.4)
≥6,000,000 418 (10.8) 534 (13.6)
Nonresponse 118 (2.9) 199 (4.8)
Residence    
Seoul 927 (23.2) 784 (19.1)
Gyeongin 1,017 (25.4) 874 (21.2)
Gangwon 168 (4.2) 196 (4.8)
Chungcheong 522 (13.0) 656 (16.0)
Honam 494 (12.3) 610 (14.8)
Yeongnam 729 (18.2) 775 (18.8)
Jeju 146 (3.6) 217 (5.3)

Values are presented as number (%).

KRW, Korean won.

Table 2.
Prevalence of allergic disease es in elementa ary school child dren (6 to 7 yea ars)
Variable Seoul Gyeongin Gangwon Chungcheong Honam Yeongnam Jeju Total P-value
Wheeze, ever 171 (18.5) 197 (19.4) 31 (18.5) 95 (18.3) 100 (20.4) 131 (18.0) 33 (22.6) 758 (19.0) 0.835
Wheeze, last 12 mo 90 (9.7) 103 (10.2) 16 (9.5) 57 (11.0) 59 (12.0) 61 (8.4) 16 (11.0) 402 (10.1) 0.532
Diagnosis of asthma, ever 87 (9.4) 91 (9.0) 18 (10.7) 48 (9.2) 62 (12.6) 91 (12.5) 11 (7.5) 408 (10.2) 0.078
Treatment of asthma, last 12 mo 33 (3.6) 41 (4.0) 5 (3.0) 17 (3.3) 24 (4.9) 29 (4.0) 5 (3.4) 154 (3.9) 0.854
Rhinitis symptoms, ever 400 (43.3) 502 (49.5) 82 (48.8) 256 (49.2) 216 (44.1) 327 (45.1) 72 (49.3) 1,855 (46.5) 0.071
Rhinitis symptoms, last 12 mo 372 (40.4) 471 (46.4) 77 (45.8) 242 (46.7) 208 (42.4) 302 (41.7) 65 (44.5) 1,737 (43.6) 0.088
Diagnosis of AR, ever 287 (31.0) 386 (38.0) 66 (39.3) 204 (39.1) 185 (37.5) 306 (42.1) 44 (30.1) 1,478 (37.0) 0.000
Treatment of AR, last 12 mo 213 (23.0) 309 (30.4) 56 (33.3) 164 (31.4) 138 (28.0) 231 (31.8) 32 (21.9) 1,143 (28.6) 0.000
Rhinitis with sensitization, last 12 mo 171 (18.4) 229 (22.5) 43 (25.6) 119 (22.8) 108 (21.9) 135 (18.5) 38 (26.0) 843 (21.1) 0.038
Itchy eczema, ever 251 (27.2) 270 (26.6) 48 (28.6) 151 (29.0) 124 (25.4) 194 (26.7) 38 (26.0) 1,076 (27.0) 0.909
Itchy flexural eczema, last 12 mo 203 (22.0) 195 (19.2) 38 (22.6) 106 (20.3) 97 (19.9) 154 (21.2) 29 (19.9) 822 (20.6) 0.796
Diagnosis of AD, ever 336 (36.4) 357 (35.2) 60 (35.9) 192 (36.9) 168 (34.1) 254 (34.8) 55 (37.7) 1,422 (35.6) 0.948
Treatment of AD, last 12 mo 143 (15.5) 163 (16.1) 31 (18.5) 70 (13.4) 76 (15.4) 107 (14.7) 20 (13.7) 610 (15.3) 0.710

Values are presented as number (%). AR, allergic rhinitis; AD, atopic dermatitis.

Table 3.
Prevalence of allergic diseases in middle school children (12 to 13 years)
Variable Seoul Gyeongin Gangwon Chungcheong Honam Yeongnam Jeju Total P-value
Wheeze, ever 146 (18.8) 138 (15.9) 37 (19.6) 94 (14.6) 90 (14.9) 98 (12.9) 31 (14.8) 634 (15.6) 0.035
Wheeze, last 12 mo 89 (11.5) 62 (7.2) 22 (11.6) 48 (7.4) 53 (8.8) 58 (7.7) 13 (6.2) 345 (8.5) 0.012
Diagnosis of asthma, ever 62 (7.9) 57 (6.6) 8 (4.2) 47 (7.3) 47 (7.7) 59 (7.7) 21 (9.9) 301 (7.4) 0.400
Treatment of asthma, last 12 mo 17 (2.2) 12 (1.4) 2 (1.1) 10 (1.5) 11 (1.8) 15 (2.0) 2 (0.9) 69 (1.7) 0.779
Rhinitis symptoms, ever 397 (50.9) 426 (49.2) 96 (50.3) 337 (51.8) 271 (44.8) 317 (41.4) 102 (48.6) 1,946 (47.9) 0.001
Rhinitis symptoms, last 12 mo 351 (45.3) 382 (44.3) 89 (46.6) 293 (45.5) 240 (39.9) 279 (36.7) 86 (42.0) 1,720 (42.6) 0.003
Diagnosis of AR, ever 245 (31.5) 272 (31.3) 55 (28.8) 218 (33.7) 148 (24.5) 204 (26.6) 71 (33.5) 1,213 (29.8) 0.003
Treatment of AR, last 12 mo 166 (21.3) 177 (20.4) 35 (18.4) 152 (23.4) 109 (18.0) 128 (16.8) 54 (25.5) 821 (20.2) 0.013
Rhinitis with sensitization, last 12 mo 222 (28.3) 259 (29.6) 54 (27.6) 207 (31.6) 158 (25.9) 183 (23.6) 61 (28.1) 1,144 (27.8) 0.029
Itchy eczema, ever 163 (21.0) 179 (20.8) 35 (18.6) 123 (19.2) 112 (18.6) 143 (18.9) 47 (22.4) 802 (19.9) 0.773
Itchy flexural eczema, last 12 mo 110 (14.1) 108 (12.6) 22 (11.7) 91 (14.3) 72 (12.0) 92 (12.2) 33 (15.8) 528 (13.1) 0.595
Diagnosis of AD, ever 206 (26.5) 213 (24.7) 49 (25.7) 155 (24.3) 136 (22.6) 169 (22.1) 50 (24.0) 978 (24.2) 0.508
Treatment of AD, last 12 mo 72 (9.3) 78 (9.1) 21 (11.1) 53 (8.3) 56 (9.3) 56 (7.3) 24 (11.4) 360 (8.9) 0.480

Values are presented as number (%). AR, allergic rhinitis; AD, atopic dermatitis.

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