Journal List > J Korean Soc Hypertens > v.20(2) > 1089821

J Korean Soc Hypertens. 2014 Jun;20(2):31-41. Korean.
Published online June 30, 2014.  https://doi.org/10.5646/jksh.2014.20.2.31
Copyright © 2014. The Korean Society of Hypertension
Blood Pressure Change and the Associated Factors in a Middle-Aged Korean Rural Population: Atherosclerosis Risk of a Rural Area Korean General Population (ARIRANG) Study
Jun-Won Lee, MD,1 Byung-Su Yoo, MD,1 Ji Hyun Lee, MD,1 Young Jin Youn, MD,1 Sung Gyun Ahn, MD,1 Min-Soo Ahn, MD,1 Jang-Young Kim, MD,1 Seung-Hwan Lee, MD,1 Jung han Yoon, MD,1 and Eun-Hui Choi, MD2
1Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
2Institute of Lifestyle Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.

Correspondence to: Byung-Su Yoo, MD. Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju 220-701, Korea. Tel: +82-33-741-0920, Fax: +82-33-741-1219, Email: yubs@yonsei.ac.kr
Received March 03, 2014; Revised March 23, 2014; Accepted June 27, 2014.

Abstract

Background

Elevation of blood pressure (BP) and the increasing incidence of hypertension have been known to be associated with time course, especially age. But there is still lack of evidence of BP change and the association with biochemical markers or markers for subclinical organ damage in Korean general population. Thus, the purpose of this study is to investigate BP change and the related factors in established Korean mid-aged rural cohort.

Methods

This study was performed by using data from ARIRANG cohort (Atherosclerosis Risk of a Rural Area Korean General Population) in Gangwon rural area. Data were collected from baseline survey (Nov 2005-Jan 2008) and follow-up survey (Apr 2008-Jan 2011). Among 5,515 participants, 1,863 were analyzed after excluding individuals with hypertension, diabetes mellitus, cerebral infarction, myocardial infarction, missing data for BP, and newly-developed hypertension.

Results

Mean age was 53.4 ± 8.2 years and men were 718 (38.5%). Mean follow-up period was 2.4 ± 0.9 years. Baseline systolic and diastolic BP were 123.6 ± 15.7 mm Hg and 79.2 ± 10.8 mm Hg. Systolic BP changes were -10.9 ± 15.3 mm Hg and diastolic BP changes were -7.7 ± 11.8 mm Hg. In logistic regression analysis, predictors for elevation of systolic BP on follow-up were start regular exercise (odds ratio [OR], 0.765; 95% confidence interval [CI], 0.604 to 0.968; p=0.0257) and fasting glucose (OR, 0.984; 95% CI, 0.972 to 0.996; p=0.0102) and homeostasis assessment-insulin resistance (OR, 0.82; 95% CI, 0.707 to 0.952; p = 0.0086).

Conclusions

Follow-up systolic and diastolic BP were significantly decreased when compared to baseline BP in mid-aged Korean rural cohort population. Long-term follow-up is needed to discriminate the periodic change of BP and the associated factors.

Keywords: Blood pressure; Cohort study; Hypertension

Tables


Table 1
Anthropometrical, laboratory and metabolic characteristics of study population
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Table 2
Characteristics of study population by quartile of systolic blood pressure change
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Table 3
Characteristics of study population by quartile of diastolic blood pressure change
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Table 4
The correlation between BP change and baseline laboratory tests
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Table 5
Logistic regression analysis for BP elevation on follow-up
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Notes

No potential conflict of interest relevant to this article was reported.

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