Comparative Effectiveness Evaluation as Outcomes Research

Jong-Myon Bae

doi:10.5646/jksh.2012.18.1.24

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Bae: Comparative Effectiveness Evaluation as Outcomes Research

Review

Journal of the Korean Society of Hypertension

Journal of the Korean Society of Hypertension 2012; 18(1): 24-28.

Published online: 31 March 2012

DOI: https://doi.org/10.5646/jksh.2012.18.1.24

Comparative Effectiveness Evaluation as Outcomes Research

Jong-Myon Bae, MD

Department of Preventive Medicine, Jeju National University School of Medicine, Jeju, Korea.

Correspondence to: jmbae@jejunu.ac.kr

Received 16 January 2012 Revised 15 February 2012 Accepted 16 February 2012

Abstract

In spite of being several results of efficacy obtained by randomized controlled trials about new health technologies, evidences related to real effectiveness confirmed by head-to-head direct comparison should be needed in order to improve qualities of healthcare. The comparative effectiveness evaluation (CEE) as outcomes research have suggested as the important tool for developing evidence-based information to patients, clinicians, and other decision makers about which technologies are most effective for which patients under specific circumstances. Four major methods of outcomes research are applied as systematic reviews and meta-analyses, cohort studies using registries, linkage of large databases, and pragmatic clinical trials. Through activating the CEE, the best and most effective technologies should be adopted rapidly in routine clinical practices.

Keywords: Outcome assessment (health care), Comparative effectiveness research, Meta-analysis, Technology assessments, biomedical

Figures and Tables

Fig. 1

The range of outcomes associated with heart failure. (A) Range of clinical outcomes associated with heart failure. (B) Integration of multiple endpoints (From Spertus JA, et al. Am Heart J. 2002;143:636-42).16)

Table 1

Several conclusions of effect of a beta-adrenergic receptor blocker in myocardial infarction

Table 2

Definitions of outcomes research (OR) and comparative effectiveness research (CER)

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