Journal List > Korean J Obstet Gynecol > v.55(12) > 1088569

Lee, Lee, Park, Cha, Park, Kim, Yang, Song, Koong, Kang, and Kim: Serum anti-Müllerian hormone levels in the patients with ovarian endometriosis undergoing surgical treatment



To evaluate the difference of serumanti-Müllerian hormone (AMH) levels in women between undergoing previous ovarian surgery with endometriosis and controls.


We reviewed medical records and evaluated the serum AMH levels of 217 women (26-40 years old) between March 2010 and January 2011, retrospectively. One hundred five patients were previously undergone the ovarian surgery of endometriosis (study group) and 112 women has never undergone ovarian surgery as controls (control group). Exclusion criteria was following factors: irregular menstruation, polycystic ovary syndrome, high BMI (≥30 kg/m2), other endocrine disease.


The mean age in study group was not different with control group (32.5 ± 3.6 vs. 33.0 ± 3.8 year). The mean serum AMH levels significantly lower in the study group than in control (2.82 ± 2.4 ng/mL vs. 3.82 ± 2.8 ng/mL, P=0.005). When we analyzed the serum AMH levels according to age groups, the patients above 31 years showed significantly lower levels than control (31-35 years, 2.41±1.7 ng/mL vs. 3.84 ± 2.6 ng/mL, P=0.005; 36-40 years, 1.36 ± 2.0 ng/mL vs. 2.68 ± 2.7 ng/mL, P=0.018) The serum AMH levels didn't show any statistical difference in aspect of bilaterality, endometriosis stage, cyst size (≥6 cm).


We could consider relatively low serum AMH levels in patients with ovarian endometriosis after surgical treatment.

Figures and Tables

Fig. 1
Serum anti-Müllerian hormone (AMH) concentration between study group and control group according to the age. Values are median (lines), 25-75th percentiles (boxes) and 95% confidence interval (whiskers). aP = 0.005, bP = 0.018.
Table 1
Basal characteristics of study population

Values are presented as mean ± standard deviation.

AMH, anti-Müllerian hormone; FSH, follicle stimulating hormone; LH, luteinizing hormone; TSH, thyroid stimulating hormone.

a,cP=0.005; b,fP=0.018; dP=0.044; eP=0.028.

Table 2
The postoperative serum AMH levels in patients with endometriosis according to the age group

Values are presented as mean ± standard deviation.

AMH, anti-Müllerian hormone; NS, not significant.


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