Journal List > Korean J Obstet Gynecol > v.55(12) > 1088565

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Lee, Bae, Lee, Kim, and Kim: Risk factors of lymphocele after RAH with pelvic lymph node dissection for women with cervical cancer
Original Article
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(12): 907-912.

Published online: 18 December 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.12.907

Risk factors of lymphocele after RAH with pelvic lymph node dissection for women with cervical cancer

Ji Yen Lee, MD, Jaeman Bae, MD, Sun-Joo Lee, MD, Ji Yeon Kim, MD, Soo Nyung Kim, MD

Department of Obstetrics and Gynecology, Konkuk University School of Medicine, Seoul, Korea.

Corresponding author: Soo Nyung Kim, MD. Department of Obstetrics and Gynecology, Konkuk University Medical Center, Konkuk University School of Medicine, 120 Neungdong-ro, Gwangjin-gu, Seoul 143-729, Korea. Tel: +82-2-2030-7641 Fax: +82-2-2030-7748, snkim@kuh.ac.kr

Received 27 April 2012       Revised 10 September 2012       Accepted 28 November 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective

To identify the risk factors of lymphocele formation in patients with cervical cancer who underwent radical abdominal hysterectomy and pelvic lymph node dissection.

Methods

We conducted a retrospective study of 62 patients diagnosed with cervical cancer who underwent radical abdominal hysterectomy, including pelvic lymph node dissection between April 2005 and June 2010. Lymphocele was confirmed by imaging studies such as computed tomography or ultrasonography. Included risk factors were patient's age, body mass index, surgeon's experience, tumor histology, stage of cancer, previous surgery, number of retrieved lymph nodes, and radiation therapy. Multiple logistic regression analysis was performed to evaluate the risk factors of lymphocele formation.

Results

During median follow-up of 34.5 months (range, 12-69 months), 20 patients (32%) out of 62 had developed lymphocele. Eight patients developed symptomatic lymphocle. Univariate analysis showed the radiation therapy, and the number of retrieved lymph nodes as significant risk factors of lymphocele formation. When applying mutivariate analysis using logistic regression, radiation therapy (odds ratio=5.19, p=0.010) and the number of retrieved lymph node (odds ratio=4.80, p=0.021) were independent risk factors of lymphocele formation.

Conclusion

Radiation therapy and the number of retrieved lymph node were significant risk factors of lymphocele formation in patients with cervical cancer who underwent radical abdominal hysterectomy and pelvic lymph node dissection.

Keywords: Lymphocele, Cervical cancer, Risk factors

Figures and Tables

Table 1
Characteristics of patients
kjog-55-907-i001
Table 2
Bivariate analyses for risk factors of lymphocele
kjog-55-907-i002

aP-value by chi-square test.

Table 3
Multivariate analysis for risk factors of lymphocele
kjog-55-907-i003

aP-value by logistic regression analysis.

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