Journal List > Korean J Obstet Gynecol > v.55(11) > 1088553

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Kang, Jin, Boo, Pyo, Oh, and Kim: Primary malignant lymphoma of the endometrium with lumbar spine involvement
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(11): 859-864.

Published online: 16 November 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.11.859

Primary malignant lymphoma of the endometrium with lumbar spine involvement

Gui Eon Kang, MD1, Sung Ah Jin, MD1, Hye Yeon Boo, MD1, Ju Yeon Pyo, MD2, Youngha Oh, MD2, Seung Ryong Kim, MD1

1Department of Obstetrics and Gynecology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.

2Department of Pathology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.

Corresponding author: Seung Ryong Kim, MD, PhD. Department of Obstetrics and Gynecology, Hanyang University Guri Hospital, Hanyang University College of Medicine, 153 Gyeongchun-ro, Guri 471-701, Korea. Tel: +82-31-560-2343, Fax: +82-31-565-2343, kimsr@hanyang.ac.kr

Received 31 May 2012       Revised 23 July 2012       Accepted 4 September 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Primary malignant lymphomas in the female genital tract are rare, but when it occurs, the cervix or the ovary are more common site than the uterine corpus. Most common symptoms are abnormal vaginal bleeding but sometimes it is symptom free. Due to rarity of primary malignant lymphoma, the standard treatments are not yet established, but rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone chemotherapy after the surgery is general executed. We present a case of primary malignant lymphoma originating from endometrium with spine involvement.

Keywords: Lymphoma, Endometrium, Uterus

Figures and Tables

Fig. 1
Positron emission tomography image; Hypermetabolic huge mass in the pelvic cavity, suggesting malignancy (arrow).
kjog-55-859-g001
Fig. 2
Gross findings of oval shaped, enlarged uterine body mass with nodular growth (A) involving entire endomyometirial wall with fish flesh, gray white mass in cut section (B).
kjog-55-859-g002
Fig. 3
Microscopic features of uterine mass. (A) Atypical lymphoid cells diffusely infiltrated in endomyometrium (H&E, ×12.5). (B) The tumor cells have moderate to large nuclei with prominent nucleoli and scanty cytoplasm (H&E, ×400). On immunohistochemical staining, the tumor cells positive for CD79a (C, immunostain, ×400) and Bcl-2 (D, immunostain, ×400).
kjog-55-859-g003
Table 1
Ann Arbor staging system for malignant lymphomas
kjog-55-859-i001

E, extralymphatic site; S, spleen involvement.

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