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Park, Yoon, Choi, Oh, Kim, and Roh: Pregnancy complicated with myelodysplastic syndrome and severe preeclampsia: A case report
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(10): 745-750.

Published online: 9 October 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.10.745

Pregnancy complicated with myelodysplastic syndrome and severe preeclampsia: A case report

Hyang Gi Park, MD, So-Yeon Yoon, MD, Suk-Joo Choi, MD, Soo-Young Oh, MD, Jong-Hwa Kim, MD, Cheong-Rae Roh, MD

Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Corresponding author: Cheong-Rae Roh, MD. Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Korea. Tel: +82-2-3410-3516, Fax: +82-2-3410-0630, crroh@skku.edu

Received 24 April 2012       Revised 11 July 2012       Accepted 11 July 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Myelodysplastic syndrome (MDS) is characterized by pancytopenia in the peripheral blood due to ineffective hematopoiesis in the bone marrow. Even though pregnancy complicated with MDS is extremely rare, it can be associated with a risk of bleeding or infection during pregnancy. Therefore, meticulous supportive care including proper transfusion of packed red blood cell or platelet concentrate and decision of timing of delivery should be provided. In this report, we present a pregnancy complicated with MDS and severe preeclampsia simultaneously with a brief review of literatures.

Keywords: Myelodysplastic syndrome, Preeclampsia, Pregnancy

Figures and Tables

Fig. 1
Peripheral blood smear showing macrocytic and hyperchromic anemia (cross), hypersegmented neutrophil (arrow) and moderate thrombocytopenia (Wright-Giemsa stain, ×1,000).
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Fig. 2
Umbilical artery Doppler velocimetry at 27 weeks 2 days of gestation. Velocimetry is zero during diastole.
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Fig. 3
The changes of blood cell count during pregnancy and postpartum period. (A) Platelet. (B) White blood cell (WBC). (C) Hemoglobin (Hb). C/Sec, Cesarean delivery; POD, postoperation day.
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