Journal List > Korean J Obstet Gynecol > v.55(10) > 1088527

TOOLS
Lee, Kim, Moon, Kim, and Bai: Correlation analysis about effect of cardiovascular risk factors and disease in women on overactive bladder and stress urinary incontinence
Original Article
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(10): 730-735.

Published online: 9 October 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.10.730

Correlation analysis about effect of cardiovascular risk factors and disease in women on overactive bladder and stress urinary incontinence

Hyo Ryun Lee, MD1, Soo Rim Kim, MD1, Yeo Jung Moon, MD2, Sei Kwang Kim, MD1, Sang Wook Bai, MD1

1Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea.

2Department of Pharmacology, Yonsei University College of Medicine, Seoul, Korea.

Corresponding author: Sang Wook Bai, MD. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea. Tel: +82-2-2228-2230, Fax: +82-2-313-8357, swbai@yuhs.ac

Received 8 February 2012       Revised 14 May 2012       Accepted 1 June 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective

The purpose of this study was to investigate associations between overactive bladder / stress urinary incontinence and cardiovascular risk factors and disease.

Methods

We performed a retrospective review of 132 women with overactive bladder and 100 women with stress urinary incontinence, enrolled at Severance Hospital. Risk factors of cardiovascular disease included age, obesity, hypertension, diabetes, impaired fasting glucose, dyslipidemia, cardiovascular disease and familial history of cardiovascular disease.

Results

The two groups had no difference with cardiovascular disease, history of cardiovascular disease, age, obesity, smoking, alcohol, hypertension, dyslipidemia, excluding diabetes. In the univariate logistic regression analysis, diabetes was associated with prevalence of overactive bladder than stress urinary incontinence. In the multiple logistic regression analysis, there was no factor which had influence on the status of urinary incontinence.

Conclusion

While most risk factors of cardiovascular disease were not associated with overactive bladder, this study suggests that diabetes may have influence to overactive bladder than stress urinary incontinence.

Keywords: Stress urinary incontinence, Overactive bladder, Cardiovascular disease

Figures and Tables

Table 1
Basal characteristics
kjog-55-730-i001

Values are presented as the mean ± standard deviation and number (%).

Pearson's chi-squared test or Fisher's exact test were used.

OAB, overactive bladder; SUI, stress urinary incontinency.

Table 2
Correlating relationships of cardiovascular disease and cardiovascular risk factors between OAB and SUI
kjog-55-730-i002

Values are presented as number (%).

Pearson's chi-squared test or Fisher's exact test were used.

OAB, overactive bladder; SUI, stress urinary incontinency.

Table 3
The univariate analysis of cardiovascular disease and cardiovascular risk factors between OAB and SUI
kjog-55-730-i003

Values are presented as odds ratio (95% confidential intervals).

OAB, overactive bladder; SUI, stress urinary incontinency; CAD, coronary artery disease; CVA, cardiovascular accident.

Table 4
The multivariate analysis of cardiovascular disease and cardiovascular risk factors between OAB and SUI
kjog-55-730-i004

Values are presented as odds ratio (95% confidential intervals).

OAB, overactive bladder; SUI, stress urinary incontinency; CVA, cardiovascular accident.

References

1. Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, et al. The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Urology. 2003. 61:37–49.
2. Botlero R, Urquhart DM, Davis SR, Bell RJ. Prevalence and incidence of urinary incontinence in women: review of the literature and investigation of methodological issues. Int J Urol. 2008. 15:230–234.
3. Hampel C, Wienhold D, Benken N, Eggersmann C, Thüroff JW. Prevalence and natural history of female incontinence. Eur Urol. 1997. 32:Suppl 2. 3–12.
4. Wagner TH, Hu TW. Economic costs of urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct. 1998. 9:127–128.
5. Olsen AL, Smith VJ, Bergstrom JO, Colling JC, Clark AL. Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstet Gynecol. 1997. 89:501–506.
6. Lee KS, Sung HH, Na S, Choo MS. Prevalence of urinary incontinence in Korean women: results of a National Health Interview Survey. World J Urol. 2008. 26:179–185.
7. Sandvik H, Hunskaar S, Vanvik A, Bratt H, Seim A, Hermstad R. Diagnostic classification of female urinary incontinence: an epidemiological survey corrected for validity. J Clin Epidemiol. 1995. 48:339–343.
8. Pearson TA, Blair SN, Daniels SR, Eckel RH, Fair JM, Fortmann SP, et al. American Heart Association Science Advisory and Coordinating Committee. AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update: Consensus Panel Guide to Comprehensive Risk Reduction for Adult Patients Without Coronary or Other Atherosclerotic Vascular Diseases. Circulation. 2002. 106:388–391.
9. Azadzoi KM, Yalla SV, Siroky MB. Oxidative stress and neurodegeneration in the ischemic overactive bladder. J Urol. 2007. 178:710–715.
10. Yoshida M, Masunaga K, Nagata T, Satoji Y, Shiomi M. The effects of chronic hyperlipidemia on bladder function in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits. Neurourol Urodyn. 2010. 29:1350–1354.
11. Choo V. WHO reassesses appropriate body-mass index for Asian populations. Lancet. 2002. 360:235.
12. DeFronzo RA, Abdul-Ghani M. Assessment and treatment of cardiovascular risk in prediabetes: impaired glucose tolerance and impaired fasting glucose. Am J Cardiol. 2011. 108:3 Suppl. 3B–24B.
13. Ryu WS, Lee SH, Kim CK, Kim BJ, Yoon BW. Body mass index, initial neurological severity and long-term mortality in ischemic stroke. Cerebrovasc Dis. 2011. 32:170–176.
14. Sanders JL, Fitzpatrick AL, Boudreau RM, Arnold AM, Aviv A, Kimura M, et al. Leukocyte telomere length is associated with noninvasively measured age-related disease: The Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2012. 67:409–416.
15. Anders K. Recent developments in stress urinary incontinence in women. Nurs Stand. 2009. S:25–27.
16. Daneshgari F, Moore C, Frinjari H, Babineau D. Patient related risk factors for recurrent stress urinary incontinence surgery in women treated at a tertiary care center. J Urol. 2006. 176:1493–1499.
17. McGrother CW, Donaldson MM, Hayward T, Matthews R, Dallosso HM, Hyde C, et al. Urinary storage symptoms and comorbidities: a prospective population cohort study in middle-aged and older women. Age Ageing. 2006. 35:16–24.
18. Waetjen LE, Liao S, Johnson WO, Sampselle CM, Sternfield B, Harlow SD, et al. Factors associated with prevalent and incident urinary incontinence in a cohort of midlife women: a longitudinal analysis of data: study of women's health across the nation. Am J Epidemiol. 2007. 165:309–318.
19. Tunn R, Goldammer K, Neymeyer J, Gauruder-Burmester A, Hamm B, Beyersdorff D. MRI morphology of the levator ani muscle, endopelvic fascia, and urethra in women with stress urinary incontinence. Eur J Obstet Gynecol Reprod Biol. 2006. 126:239–245.
20. Kim JC, Joo KJ, Kim JT, Choi JB, Cho DS, Won YY. Alteration of autonomic function in female urinary incontinence. Int Neurourol J. 2010. 14:232–237.
TOOLS
Similar articles