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Mo, Sung, Kyung, Cho, Ro, and Choi: A case of mullerian adenosarcoma of the uterus
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(9): 678-682.

Published online: 17 September 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.9.678

A case of mullerian adenosarcoma of the uterus

A Jin Mo, MD1, Ji Eun Sung, MD1, Min Sun Kyung, MD1, Yong Cho, MD1, Eu Sun Ro, MD1, Kyung Chan Choi, MD2

1Department of Obstetrics and Gynecology, Hallym University College of Medicine, Chuncheon, Korea.

2Department of Pathology, Hallym University College of Medicine, Chuncheon, Korea.

Corresponding author: Eu Sun Ro, MD. Department of Obstetrics and Gynecology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, 77 Sakju-ro, Chuncheon 200-704, Korea. Tel: +82-33-240-5162, Fax: +82-33-252-9974, esr@hallym.or.kr

Received 30 April 2012       Revised 9 June 2012       Accepted 21 June 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Mullerian adenosarcoma which is characterized by admixture of benign-appearing neoplastic glands and sarcomatous stroma, is an uncommon variant of malignant mixed mullerian tumor (MMMT). Classic treatment for this rare tumor is hysterectomy with bilateral salpingo-oophorectomy. Its prognosis is relatively poor, but better than MMMT. The efficacy of adjuvant postoperative radiotherapy and chemotherapy is debatable and appears not to be promising. We report a 62-year-old female with mullerian adenosarcoma diagnosed after hysterectomy with bilateral salpingo-oophorectomy, which had shown unique ultrasonographic feature like hydatidiform mole and had been diagnosed as fibroadenoma in endometrial curettage, with brief review of literatures.

Keywords: Mullerian adenosarcoma, Malignant mixed mullerian tumor, Uterine sarcoma

Figures and Tables

Fig. 1
A mixed echogenic mass of 6.3 × 4.4 cm which is mimic to Hydatidiform mole in transvaginal ultrasonogram.
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Fig. 2
A polypoid lesion in the uterine cavity, measuring 6 × 5 cm. The cut surface of the lesion was multilobular and cystic.
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Fig. 3
Histopathological findings of endometrial curettage specimen (H&E, ×100). Fibrous and myxoid stroma surrounding endometrial gland, which is compatible with fibroadenoma.
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Fig. 4
Histopathological findings of hysterectomy specimen (H&E, ×100). The surface of this tumor has a leaf-like appearance with hypercellular stroma.
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Fig. 5
Histopathological findings of hysterectomy specimen (H&E, ×400). Cuffing of hypercellular stroma surrounding compressed slit-like glands is seen. Also mitotic figure of stromal cells can be observed (arrow).
kjog-55-678-g005

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