Journal List > Korean J Obstet Gynecol > v.55(9) > 1088516

Yi, Shin, Je, Lee, and Baik: A case of primary ovarian low-grade endometrial stromal sarcoma

Abstract

Endometrial stromal sarcoma (ESS) is a relatively rare form of uterine sarcoma. ESS of the myometrium compose just 0.2% of uterine malignant tumors. Low-grade ESS has extended beyond the uterus in 40% of cases at the time of diagnosis. ESS of ovary is very rare. Most of ovarian ESS is concomitant with endometriosis or same tumor in uterus. We have experienced a primary ovarian low-grade ESS, and that sarcoma is localized in ovary. So, we report this case with review of literature.

Figures and Tables

Fig. 1
Abdominal computed tomography (CT). Coronal (A) and horizontal (B) CT showing mixed density 11.6×9.2 cm solid mass (arrow) in pelvic cavity, abutting uterus with poor enhancements.
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Fig. 2
Transvaginal ultrasonography shows mixed echogenic solid mass in pelvic cavity.
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Fig. 3
Dense cellular neoplasm, composed of ovoid cells with interspersed small arterioles (H&E, ×40).
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Fig. 4
The ovoid tumor cells are arranged concentrically around the spiral arterioles (H&E, ×200).
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Fig. 5
Interstitial hemorrhage and congestion, due to torsion (H&E, ×200).
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References

1. Baiocchi G, Kavanagh JJ, Wharton JT. Endometrioid stromal sarcomas arising from ovarian and extraovarian endometriosis: report of two cases and review of the literature. Gynecol Oncol. 1990. 36:147–151.
2. Harlow BL, Weiss NS, Lofton S. The epidemiology of sarcomas of the uterus. J Natl Cancer Inst. 1986. 76:399–402.
3. Young RH, Prat J, Scully RE. Endometrioid stromal sarcomas of the ovary. A clinicopathologic analysis of 23 cases. Cancer. 1984. 53:1143–1155.
4. Chang KL, Crabtree GS, Lim-Tan SK, Kempson RL, Hendrickson MR. Primary uterine endometrial stromal neoplasms. A clinicopathologic study of 117 cases. Am J Surg Pathol. 1990. 14:415–438.
5. Fukunaga M, Ishihara A, Ushigome S. Extrauterine low-grade endometrial stromal sarcoma: report of three cases. Pathol Int. 1998. 48:297–302.
6. Oliva E, Clement PB, Young RH. Endometrial stromal tumors: an update on a group of tumors with a protean phenotype. Adv Anat Pathol. 2000. 7:257–281.
7. Berek JS, Novak E. Berek & Novak's gynecology. 2012. 15th ed. Philadelphia (PA): Lippincott Williams & Wilkins.
8. Piver MS, Rutledge FN, Copeland L, Webster K, Blumenson L, Suh O. Uterine endolymphatic stromal myosis: a collaborative study. Obstet Gynecol. 1984. 64:173–178.
9. Franquemont DW, Frierson HF Jr, Mills SE. An immunohistochemical study of normal endometrial stroma and endometrial stromal neoplasms. Evidence for smooth muscle differentiation. Am J Surg Pathol. 1991. 15:861–870.
10. Nordal RR, Kristensen GB, Kaern J, Stenwig AE, Pettersen EO, Tropé CG. The prognostic significance of surgery, tumor size, malignancy grade, menopausal status, and DNA ploidy in endometrial stromal sarcoma. Gynecol Oncol. 1996. 62:254–259.
11. Gloor E, Schnyder P, Cikes M, Hofstetter J, Cordey R, Burnier F, et al. Endolymphatic stromal myosis. Surgical and hormonal treatment of extensive abdominal recurrence 20 years after hysterectomy. Cancer. 1982. 50:1888–1893.
12. Baker VV, Walton LA, Fowler WC Jr, Currie JL. Steroid receptors in endolymphatic stromal myosis. Obstet Gynecol. 1984. 63:72S–74S.
13. Lehrner LM, Miles PA, Enck RE. Complete remission of widely metastatic endometrial stromal sarcoma following combination chemotherapy. Cancer. 1979. 43:1189–1194.
14. Blom R, Malmström H, Guerrieri C. Endometrial stromal sarcoma of the uterus: a clinicopathologic, DNA flow cytometric, p53, and mdm-2 analysis of 17 cases. Int J Gynecol Cancer. 1999. 9:98–104.
15. Bodner K, Bodner-Adler B, Obermair A, Windbichler G, Petru E, Mayerhofer S, et al. Prognostic parameters in endometrial stromal sarcoma: a clinicopathologic study in 31 patients. Gynecol Oncol. 2001. 81:160–165.
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