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Yun, Kim, and Lee: Postirradiation malignant fibrous histiocytoma of the vulva and vagina following recurrent cervix cancer
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(8): 596-600.

Published online: 17 August 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.8.596

Postirradiation malignant fibrous histiocytoma of the vulva and vagina following recurrent cervix cancer

Hang Goo Yun, MD, Jin Ha Kim, MD, Tae Hwa Lee, MD

Department of Obstetrics and Gynecology, Kosin University College of Medicine, Busan, Korea.

Corresponding author: Tae Hwa Lee, MD. Department of Obstetrics and Gynecology, Kosin University College of Medicine, 262 Gamcheon-ro, Seo-gu, Busan 602-702, Korea. Tel: +82-51-990-6722, Fax: +82-51-244-6939, leehula@hanmail.net

Received 4 April 2012       Revised 11 June 2012       Accepted 3 July 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We describe here the case of a 65-year-old women presenting with a hemorrhagic tumor around the anterior vaginal wall and vulva. She was diagnosed with malignant fibrous histiocytoma from the findings of cytological analysis of biopsied surface tissue, histopathologic analysis of biopsied, and immunohistochemical staining. In her past history, twenty years ago, she was diagnosed with cervical cancer, staging Ib and received surgical treatment and chemotherapy. Ten years ago, she received radiotherapy because of recurrence of cervical cancer in vaginal vault. After surgical excision for malignant fibrous histiocytoma, we recommended chemotherapy but she refused. After 24 months from initial diagnosis, she died.

Keywords: Malignant fibrous histiocytoma, Radiotherapy, Recurrent cervical cancer

Figures and Tables

Fig. 1
Preoperative appearance of malignant fibrous histiocytoma was noted around the urethral orifice, urethral stenosis due to pressed the mass. Size 3×4 cm.
kjog-55-596-g001
Fig. 2
Gross finding, including mass removed, appearance of anterior vaginal wall and vulva that are removed.
kjog-55-596-g002
Fig. 3
Microscopic findings of malignant fibrous histiocytoma show fascicles of plump spindle cells in a swirling (storiform) pattern, typical but not pathognomic pattern of this neoplasm. (A) H&E, ×100. (B) Vitamin, ×100.
kjog-55-596-g003
Table 1
Malignant fibrous histiocytoma of the vulva and vagina
kjog-55-596-i001

NED, no evidence of disease.

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