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Yoon, Lee, and Kim: Undifferentiated sarcoma arising in a mature cystic teratoma of the ovary
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(8): 582-585.

Published online: 17 August 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.8.582

Undifferentiated sarcoma arising in a mature cystic teratoma of the ovary

Hang Goo Yoon, MD1, Eun Sil Lee, MD2, Heung Yeol Kim, MD1

1Department of Obstetrics and Gynecology, Kosin University College of Medicine, Pusan, Korea.

2Department of Obstetrics and Gynecology, Soonchunhyang University College of Medicine, Seoul, Korea.

Corresponding author: Heung Yeol Kim, MD, PhD. Department of Obstetrics and Gynecology, Kosin University College of Medicine, 262 Gamcheon-ro, Seo-gu, Busan 602-702, Korea. Tel: +82-51-990-6226, Fax: +82-51-990-3300, hykyale@yahoo.com

Received 10 January 2012       Revised 6 April 2012       Accepted 24 April 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Malignant transformation within a mature cystic teratoma occurs in less than 2% of cases and most commonly results in a squamous cell carcinoma. Other reported malignancies include adenocarcinoma, various pure sarcomas, melanomas and basal cell carcinomas, and anaplastic carcinoma. We report a rare case of a 46-year-old woman with undifferentiated sarcoma arising in a teratoma of the ovary.

Keywords: Malignant transformation, Ovary, Sarcoma, Teratoma

Figures and Tables

Fig. 1
Computed tomography of the left ovarian mass showed multiseptated cyst containing fat fluid, hair and calcification with internal solid portion. Dirty infiltration is shown around the fat plane.
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Fig. 2
The positron emission tomography study demonstrated extensive bone metastasis of left ovarian cancer.
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Fig. 3
(A) Gross appearance of left ovary. 13 × 9 × 7 cm sized lobulated mass contained mixed solid and cystic components. (B) About a half of the mass is occupied by conglomerated hair shafts and two teeth are also seen. (C) H&E staining for ovarian sarcoma. There are mature teratoma components (×100). (D) Diffuse infiltration of pleomorphic, multinucleated giant cells without organoid pattern was observed, that means high grade undifferentiated sarcoma (×400).
kjog-55-582-g003

References

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