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Journal List > Korean J Obstet Gynecol > v.55(8) > 1088497

Yoon, Lee, and Kim: Undifferentiated sarcoma arising in a mature cystic teratoma of the ovary

Abstract

Malignant transformation within a mature cystic teratoma occurs in less than 2% of cases and most commonly results in a squamous cell carcinoma. Other reported malignancies include adenocarcinoma, various pure sarcomas, melanomas and basal cell carcinomas, and anaplastic carcinoma. We report a rare case of a 46-year-old woman with undifferentiated sarcoma arising in a teratoma of the ovary.

Figures and Tables

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Fig. 1
Computed tomography of the left ovarian mass showed multiseptated cyst containing fat fluid, hair and calcification with internal solid portion. Dirty infiltration is shown around the fat plane.

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Fig. 2
The positron emission tomography study demonstrated extensive bone metastasis of left ovarian cancer.

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Fig. 3
(A) Gross appearance of left ovary. 13 × 9 × 7 cm sized lobulated mass contained mixed solid and cystic components. (B) About a half of the mass is occupied by conglomerated hair shafts and two teeth are also seen. (C) H&E staining for ovarian sarcoma. There are mature teratoma components (×100). (D) Diffuse infiltration of pleomorphic, multinucleated giant cells without organoid pattern was observed, that means high grade undifferentiated sarcoma (×400).

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References

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