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Kang, Kwon, Sohn, and Hwang: The risk factor related with small for gestational age in term delivery women with an episode of preterm labor
Original Article
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(5): 293-299.

Published online: 16 May 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.5.293

The risk factor related with small for gestational age in term delivery women with an episode of preterm labor

Hyun Jung Kang, MD, Han Sung Kwon, MD, In Sook Sohn, MD, Han Sung Hwang, MD

Department of Obstetrics and Gynecology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.

Corresponding author: Han Sung Hwang, MD. Department of Obstetrics and Gynecology, Konkuk University Medical Center, Konkuk University School of Medicine, 120 Neungdong-ro, Gwangjin-gu, Seoul 143-729, Korea. Tel: +82-2-2030-7648, Fax: +82-2-2030-7748, 20080251@kuh.ac.kr

Received 27 October 2011       Revised 20 December 2011       Accepted 26 January 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective

The aim of this study was to investigate the potential prognostic factors and it's relating factors of patients who were hospitalized for management of preterm labor.

Methods

In this study, we retrospectively reviewed the records of 249 mothers who experienced the admission of preterm labor and delivered single live birth from January 2005 to May 2011 at our hospital. For our analyses, the mothers were divided into two groups according to delivery age; preterm birth group and full term birth group. And full term birth group was divided into two groups which had poor prognostic factors and compared with each other groups.

Results

In our cohort, there was high incidence of small for gestational age in full term birth group compared with preterm birth group significantly (19.6% vs. 9.4%; P=0.028). And potential factors related to small for gestational age in full term birth group were early gestational age at 1st admission, low body mass index (BMI) in mothers and high highly sensitive C-reactive protein (hs-CRP) at 1st admission.

Conclusion

Gestational age at 1st admission, mother's BMI and hs-CRP at admission were significantly related to small for gestational age in full term birth who were hospitalized for management of preterm labor.

Keywords: Preterm labor, Small for gestational age, Highly sensitive C-reactive protein

Figures and Tables

Fig. 1
The risk factors associated with SGA between two groups in term delivery women with preterm episode. (A) Gestational week at preterm admission was significantly earlier at SGA delivery group compared with non-SGA. (B) BMI in SGA delivery group was significantly lower than non-SGA. (C) The level of hs-CRP in SGA delivery group was higher than non-SGA. SGA, small for gestational age; BMI, body mass index; hs-CRP, highly sensitive C-reactive protein.
kjog-55-293-g001
Table 1
Clinical characteristics of participants in delivery time between term and preterm delivery group
kjog-55-293-i001

Values are presented as number (%) or median (range)

NS, not significant; BMI, body mass index; SGA, small for gestational age.

aP<0.05 by the Student's t-test and the χ2 test.

Table 2
Clinical characteristics of participants in time admitted with the episode of preterm labor between term and preterm delivery group
kjog-55-293-i002

Values are presented as number (%) or median (range).

NS, not significant; hs-CRP, highly sensitive C-reactive protein.

aP<0.05 by the Student's t-test and the χ2 test.

Table 3
Demographic and clinical data in time admitted with an episode of preterm labor between pregnant women with and without SGA in term delivery group
kjog-55-293-i003

Values are presented as number (%) or median (range).

SGA, small for gestational age; NS, not significant; BMI, body mass index; hs-CRP, highly sensitive C-reactive protein.

aP<0.05 by the Mann-Whitney U test and the Fisher's exact test.

Table 4
Multivariable logistic regression indicating risk factors independently associated with small for gestational age in term delivery group
kjog-55-293-i004

BMI, body mass index; hs-CRP, highly sensitive C-reactive protein.

aP<0.05 by multivariable logistic regression.

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