Journal List > Korean J Obstet Gynecol > v.55(4) > 1088433

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Choi, Lee, Kim, Jeon, Kim, Bae, and Kim: A case of spindle cell carcinoma of the uterine cervix
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(4): 265-268.

Published online: 17 April 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.4.265

A case of spindle cell carcinoma of the uterine cervix

Sl-A Choi, MD1, Mi-Ra Lee, MD1, Min-Jeong Kim, MD1, Hye-Ji Jeon, MD1, Yun-Sook Kim, MD1, Dong-Han Bae, MD1, Chang-Jin Kim, MD2

1Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.

2Department of Pathology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.

Corresponding author: Yun-Sook Kim, MD. Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, 8 Soonchunhyang 2-gil, Dongnam-gu, Cheonan 330-930, Korea. Tel: +82-41-570-2150, Fax: +82-41-571-7887, drsook@schmc.ac.kr

Received 2 December 2011       Revised 19 January 2012       Accepted 16 February 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Spindle cell carcinoma is a rare variant of squamous cell carcinoma characterized histologically by a biphasic pattern with both squamous and spindle cell component. There is controversy in the histogenesis, biologic behavior, optimal treatment and prognostic factor for tumor. Treatment must be similar for squamous cell carcinoma. With a review of literature, we report a case of a 52-year-old female with spindle cell carcinoma in the uterine cervix, which has been managed by total hysterectomy.

Keywords: Spindle cell carcinoma, Uterine cervix, Hysterectomy

Figures and Tables

Fig. 1
Punch biopsy reveals carcinoma composed of spindle cells (H&E, ×200).
kjog-55-265-g001
Fig. 2
(A) Cone biopsy of the cervix shows squamous cell carcinoma, focal fascicles of proliferating spindle cell, which considerable mitotic activity, and focal moderate degree of nuclear atypia (H&E, ×400). (B) Immunohistochemical finding shows positive reaction for smooth muscle actin (smooth muscle antigen, ×400).
kjog-55-265-g002

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