Journal List > Korean J Obstet Gynecol > v.55(12) > 1088392

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Ko, Kim, Park, Jeon, Kim, Rhim, Kang, and Park: A case of ovarian cancer developed in Mayer-Rokitansky-Küster-Hauser syndrome: Innate carcinogenesis of ovarian cancer
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2012; 55(12): 1001-1005.

Published online: 18 December 2012

DOI: https://doi.org/10.5468/KJOG.2012.55.12.1001

A case of ovarian cancer developed in Mayer-Rokitansky-Küster-Hauser syndrome: Innate carcinogenesis of ovarian cancer

A Ra Ko, MD, Ji-Hyun Kim, MD, Sue-Ye Park, MD, Young Eun Jeon, MD, Sung Joo Kim, MD, Chae Chun Rhim, MD, Jung Bae Kang, MD, Young-Han Park, MD

Department of Obstetrics and Gynecology, Hallym University College of Medicine, Chuncheon, Korea.

Corresponding author: Young-Han Park, MD. Department of Obstetrics and Gynecology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, 22 Gwanpyeong-ro 170beon-gil, Dongan-gu, Anyang 431-796, Korea. Tel: +82-31-380-3820 Fax: +82-31-380-1900, drparkyh@yahoo.co.kr

Received 21 April 2012       Revised 28 August 2012       Accepted 12 September 2012

Copyright © 2012. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Vaginal aplasia is an unusual congenital anomaly of the genital tract with an incidence of 1 in 4,000 female births. The vast majority of the cases are part of Mayer-Rokitansky-Küster-Hauser syndrome (MRKHs). In this syndrome, while the vagina is absent and the uterus is missing or extremely rudimentary, the ovarian function is normal and the secondary sexual characteristics are normally developed. The aim of the study is to present a case of ovarian cancer that developed on the ovary of a woman with MRKH syndrome.

Keywords: Mayer-Rokitansky-Küster-Hauser syndrome, Ovarian cancer, Absent vagina

Figures and Tables

Fig. 1
A computed tomography scan shows rim-enhancing ovarian mass with solid part in pelvic cavity in patient with Mayer-Rokitansky-Küster-Hauser syndrome.
kjog-55-1001-g001
Fig. 2
Right ovary contains solid nodule composed of gray tan friable tissue and multiple cysts which are filled with serous and hemorrhagic fluid. Two triangular small rudimentary uteruses are seen in the center.
kjog-55-1001-g002
Fig. 3
Serous carcinoma of the ovary illustrates poor differentiation (H&E, ×100).
kjog-55-1001-g003

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