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Lee, Kang, Kim, and Park: The prevalence of human papilloma virus infections according to Pap smear results in Jeju island
Original Article
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2011; 54(11): 689-695.

Published online: 23 November 2011

DOI: https://doi.org/10.5468/KJOG.2011.54.11.689

The prevalence of human papilloma virus infections according to Pap smear results in Jeju island

Geun Hwa Lee, PhD1, Ho Jeong Kang, MD2, Sung Yob Kim, MD, PhD2, Chul Min Park, MD, PhD2

1Department of Microbiology, Jeju National University School of Medicine, Jeju, Korea.

2Department of Obstetrics and Gynecology, Jeju National University School of Medicine, Jeju, Korea.

Corresponding author: Chul Min Park, MD, PhD. Department of Obstetrics and Gynecology, Jeju National University School of Medicine, Ara 1-dong, Jeju 690-767, Korea. Tel: +82-64-717-1820, Fax: +82-64-717-1802, obgymd@gmail.com

Received 2 June 2011       Revised 1 August 2011       Accepted 8 September 2011

Copyright © 2011. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective

We analyzed subtypes of human papilloma virus (HPV) infection in Papanicolaou (Pap) smear results of women in Jeju island, Korea.

Methods

We investigated the distribution of HPV subtypes according to Pap smear results among 635 women in Jeju island, Korea between October 2005 and October 2010.

Results

The most prevalent HPV subtypes were HPV 16, 52, 53, 58 in negative Pap smear result and HPV 16, 52, 31, 53, 66 in atypical squamous cell, HPV 52, 53, 56, 66 in low grade squamous intraepithelial lesion, HPV 16, 58, 52, 33, 33 in high grade squamous intraepithelial lesion/squamous cell carcinoma each other. The subtypes of HPV 16, 52, 53, 58, 31 were common in all women participated in study from Jeju island, Korea. And multiple infections were more common in women under 30 years of age than above age as previous study and the majority of HPV multiple infections were high risk types (94.5%).

Conclusion

This prevalence was some different from previous study of Korean other region, but more similar to Japanese study data. We think this result shows that Jeju island women maybe have the genetic, regional or environmental close relationship with Japanese because of close distance and culture irrespective of different national race.

Keywords: Human papillomavirus, Papanicolaou smear, Jeju island

Figures and Tables

Fig. 1
Prevalence of human papilloma virus (HPV) high risk subtypes of all patients 635.
kjog-54-689-g001
Table 1
HPV prevalence according to different Pap smear results
kjog-54-689-i001

Values are presented as number (%).

HPV, human papilloma virus; Pap, Papanicolaou; HR, high risk; LR, low risk; ASC, atypical squamous cell; LSIL, low-grade squamous intraepithelial lesions; HSIL, high-grade squamous intraepithelial lesions; SCC, squamous cell carcinoma.

Table 2
Multiple HPV prevalence according to different age
kjog-54-689-i002

Values are presented as number (%).

HPV, human papilloma virus; HR, high risk; LR, low risk.

Table 3
HPV risk types according to different Pap smear results
kjog-54-689-i003

Values are presented as number (%).

HPV, human papilloma virus; Pap, Papanicolaou; ASC, atypical squamous cell; LSIL, low-grade squamous intraepithelial lesions; HSIL, high-grade squamous intraepithelial lesions; SCC, squamous cell carcinoma; HR, high risk; LR, low risk; OR, other risk.

Table 4
HPV high risk subtypes according to different Pap smear results
kjog-54-689-i004

Values are presented as number (%).

HPV, human papilloma virus; Pap, Papanicolaou; ASC, atypical squamous cell; LSIL, low-grade squamous intraepithelial lesions; HSIL, high-grade squamous intraepithelial lesions; SCC, squamous cell carcinoma.

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