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Ha, Lee, and Lee: Gastrointestinal stromal tumor in vagina: A case report
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2011; 54(10): 639-642.

Published online: 19 October 2011

DOI: https://doi.org/10.5468/KJOG.2011.54.10.639

Gastrointestinal stromal tumor in vagina: A case report

Seung Yeon Ha, MD1, Ki Beom Lee, MD2, Soon Pyo Lee, MD2

1Department of Pathology, Gachon University Gil Hospital, Incheon, Korea.

2Department of Obstetrics and Gynecology, Gachon University Gil Hospital, Incheon, Korea.

Corresponding author: Soon Pyo Lee, MD. Department of Obstetrics and Gynecology, Gachon University Gil Hospital, 1198 Guwol-dong, Namdong-gu, Incheon 405-760, Korea. Tel: +82-32-460-3078, Fax: +82-32-460-3073, syha@gilhospital.com

Received 31 May 2011       Accepted 29 July 2011

Copyright © 2011. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor that usually arises within the gastrointestinal tract. However extragastrointestinal stromal tumor (EGIST) is a rare tumor (5%), especially few cases of EGIST arising in vagina have currently been reported in the literature. We have experienced a case of vaginal GIST. A 49-year-old female presented with vaginal mass for three weeks. The mass was located posterolateral vagina near to introitus and 3.0 × 2.5 cm in size. Histological examination showed hypercelluar spindle cell proliferation and more than 10 mitoses per 50 high power fields. They were positive for c-kit (CD 117) and CD34. Surgery is the most effective treatment and long term follow up is warranted.

Keywords: Gastrointestinal stromal tumor, Vagina

Figures and Tables

Fig. 1
Transvaginal ultrasonography shows a 3.0 × 2.5 cm sized solid mass in the posterolateral vagina with increased vascularity.
kjog-54-639-g001
Fig. 2
There are bundles of hypercellular spindle cells with frequent mitosis (A: H&E, ×200). The tumor cells are positive for c-kit (B: c-kit, ×200) and CD34 (C: CD34, ×200).
kjog-54-639-g002
Table 1
Review of clinicopathologic characteristics for gastrointestinal tumor in vagina and rectovaginal septum including current case
kjog-54-639-i001

ND, not described.

aSurgery: resection of rectum with total hysterectomy and excision of posterior vagina.

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