Lymphogranuloma venereum (LGV) is a rare sexually transmitted disease caused by chlamydia trachomatis serotypes L1-L3. The peak incidence occurs in persons 29 to 47 years old, and men are six times more likely than women to manifest clinical infection. The disease clinically manifests in three stages: a primary lesion consisting of a superficial ulcer or erosion, a secondary stage with prominent lymphadenopathy and a later stage with disease manifestations such as fibrosis, fistula, and anorectal strictures. The diagnosis of LGV is based on clinical suspicion, epidemiologic information, and the exclusion of other causes of inguinal lymphadenopathy. Diagnosis of LGV may be difficult. Patients with a clinical syndrome consistent with LGV, including genital ulcer with lymphadenopathy, should be treated for LGV. Recently we have experienced a case of LGV in 44-years-old women with inguinal bubo and sclerosing fibrous skin. We treated her with doxycycline and advancement flap.