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Bae, Lim, Rhee, Kim, and Park: An orbital hemangioendothelioma of fetus detected by prenatal ultrasonography
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2011; 54(8): 464-467.

Published online: 25 August 2011

DOI: https://doi.org/10.5468/KJOG.2011.54.8.464

An orbital hemangioendothelioma of fetus detected by prenatal ultrasonography

Jin-Gon Bae, MD, Su-Yeon Lim, MD, Jeong-Ho Rhee, MD, Jong-In Kim, MD, Joon-Cheol Park, MD

Department of Obstetrics and Gynecology, Keimyung University School of Medicine, Daegu, Korea.

Corresponding author: Joon-Cheol Park, MD. Department of Obstetrics and Gynecology, Keimyung University Dongsan Medical Center, 56 Dalseong-ro, Jung-gu, Daegu 700-712, Korea. Tel: +82-53-250-7599, Fax: +82-53-250-7599, jcpark@dsmc.or.kr

Received 19 May 2011       Accepted 24 June 2011

Copyright © 2011. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Most orbital tumors of infants include retinoblastoma, dermoid cyst (teratoma), optic nerve glioma and nevus, and hemangioendothelioma is found in rare cases. Hemangioendothelioma, the tumor of intermediate malignancy between angiosarcoma and hemangioma, is commonly recognized in soft tissue of extremities, skin, lung and liver with symptoms of ulceration and hepatomegaly in neonates and infants. However it seldom localizes in the orbit. Although there have been two case reports of orbital hemangioendothelioma in neonate and adult in Korea, there was no case report of prenatally diagnosed orbital hemangioendothelioma in fetus. We found hemangioma-like orbital tumor in a fetus at 36 weeks of gestation by prenatal ultrasonography and confirmed hemangioendothelioma by microscopic examination after birth. This is the first case of orbital hemangioendothelioma in fetus.

Keywords: Orbit, Hemangioendothelioma, Ultrasonography, prenatal

Figures and Tables

Fig. 1
At 36 weeks, ultrasonography reveals 6.5 × 4.8 cm sized mass on left frontal area of fetal head.
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Fig. 2
3D-ultrasonography shows heterogenous mass on left orbital area of a 36 weeks old fetus.
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Fig. 3
Fetal magnetic resonance image shows a relatively well-definded, huge, heterog-enous, solid mass involving the left orbit, infratemporal fossa, epidural space of left frontal and temporal lobe of a fetus, measuring 82×62×75 mm (arrow). The mass is highly vascular, internal hemorrhagic and tiny calcified foci. Several large draining vessels are noted.
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Fig. 4
After birth we defined huge orbital mass occupying left orbit and left frontotemporal area of a newborn infant.
kjog-54-464-g004

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