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Lee, Lee, and Koh: A case of recurrent angiomyofibroblastoma of the vulva
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2011; 54(6): 322-325.

Published online: 30 June 2011

DOI: https://doi.org/10.5468/KJOG.2011.54.6.322

A case of recurrent angiomyofibroblastoma of the vulva

Dae Hyung Lee, MD, Jung Ju Lee, MD, Min Whan Koh, MD, PhD

Department of Obstetrics and Gynecology, Yeungnam University School of Medicine, Daegu, Korea.

Corresponding author: Min Whan Koh, MD, PhD. Department of Obstetrics and Gynecology, Yeungnam University School of Medicine, 317-1 Daemyung 5-dong, Nam-gu, Daegu 705-717, Korea. Tel: +82-53-620-3433, Fax: +82-53-654-0676, kohmw@ynu.ac.kr

Received 18 April 2011       Revised 2 May 2011       Accepted 3 May 2011

Copyright © 2011. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Angiomyofibroblastoma is a rare benign soft tissue tumor of female genital tract. It is considered to be slowly growing, of low potency for local recurrence. We recently experienced a recurrent angiomyofibroblastoma of the vulva. So, we report a recurrent case of angiomyofibroblastoma after local excision 8 years ago.

Keywords: Angiomyofibroblastoma, Recurrence

Figures and Tables

Fig. 1
About 4.5 × 1.4 cm sized sausage-shaped, elongated solid mass lesion is seen in left vulva. About 7.5 cm sized mass lesion is seen in uterus. About 2.5 and 1 cm sized two hemorrhagic cystic lesions are seen in right adnexa. About 1.5 cm sized crescentic cystic lesion is seen in rigth lateral aspect of urethra.
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Fig. 2
The tumor shows alternating hypercellular and hypocellular areas associated with prominent vascular pattern (H&E, ×40).
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Fig. 3
The tumor cells show bland-looking oval to round epithelioid appearance (H&E, ×100).
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Fig. 4
Immunoreactivities for desmin, estrogen receptor (ER) and progesterone receptor (PR) are evident, however, negative for actin (Immunohistochemistry, ×200). Desmin (A). A-smooth muscle actin (B). ER (C). PR (D).
kjog-54-322-g004

References

1. Fletcher CD, Tsang WY, Fisher C, Lee KC, Chan JK. Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma. Am J Surg Pathol. 1992. 16:373–382.
2. Park DY, Kim JY, Kim OH, Lee HS, Sol MY, Suh KS, et al. Recurred angiomyofibroblastoma of the vulva: report of a case. Korean J Pathol. 1996. 30:947–950.
3. Saleh MM, Yassin AH, Zaklama MS. Recurrent angiomyofibroblastoma of the vagina: a case report. Eur J Gynaecol Oncol. 2007. 28:324.
4. Banerjee K, Datta Gupta S, Mathur SR. Vaginal angiomyofibroblastoma. Arch Gynecol Obstet. 2004. 270:124–125.
5. Tochika N, Takeshita A, Sonobe H, Matsumoto M, Kobayashi M, Araki K. Angiomyofibroblastoma of the vulva: report of a case. Surg Today. 2001. 31:557–559.
6. Steeper TA, Rosai J. Aggressive angiomyxoma of the female pelvis and perineum. Report of nine cases of a distinctive type of gynecologic soft-tissue neoplasm. Am J Surg Pathol. 1983. 7:463–475.
7. Granter SR, Nucci MR, Fletcher CD. Aggressive angiomyxoma: reappraisal of its relationship to angiomyofibroblastoma in a series of 16 cases. Histopathology. 1997. 30:3–10.
8. Sasano H, Date F, Yamamoto H, Nagura H. Angiomyofibroblastoma of the vulva: case report with immunohistochemical, ultrastructural and DNA ploidy studies and a review of the literature. Pathol Int. 1997. 47:647–650.
9. Enzinger FM, Weiss SW. Soft tissue tumor. 1995. 3rd ed. St. Louis: Mosby.
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