Journal List > Korean J Obstet Gynecol > v.54(5) > 1088280

Park, Cho, Lee, Shin, Lee, Lee, and Paik: Prenatal diagnosis of caudal regression syndrome: A case report


Caudal regression syndrome is rare congenital defect, characterized by the absence of the sacrum, and defects of variable portion of lumbar spine, associated with anomalies from different systems. Although hyperglycemia related to maternal diabetes, genetic predisposition, teratogens, and vascular anomalies altering blood flow have been hypothesized to play a role in its pathogenesis, but the cause of this rare condition is not clear. We report a case of caudal regression syndrome diagnosed by prenatal ultrasonography at 16 weeks of gestation.

Figures and Tables

Fig. 1
(A) Transabdominal sonography shows abrupt termination of spine at lumbosacral level (arrow). (B) A 3-Dimensional mode image showing that the vertebral column ends at the lumbar level (arrow).
Fig. 2
Infantogram shows absence of lumbosacral vertebrae (arrow), frog-like position of the Rt. lower extremities, Lt. knee dislocation and absence of Lt. foot bone (open arrow).


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